GO:0030122: AP-2 adaptor complex (Cellular component)

"A heterotetrameric AP-type membrane coat adaptor complex that consists of alpha, beta2, mu2 and sigma2 subunits, and links clathrin to the membrane surface of a vesicle, and the cargo receptors during receptor/clathrin mediated endocytosis. Vesicles with AP-2-containing coats are normally found primarily near the plasma membrane, on endocytic vesicles. In at least humans, the AP-2 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different alpha genes (alphaA and alphaC)." [GOC:mah, PMID:10611976, PMID:21097499, PMID:22022230, PMID:24322426]


There are 370 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_230 Solanum tuberosum Agria 1.22 % 0.003487 0.01833
Cluster_814 Solanum tuberosum Agria 50.0 % 0.001074 0.012533
Cluster_173 Solanum tuberosum Agria 1.85 % 0.001535 0.014661
Sequences (370) (download table)

Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro Domains

Family Terms