GO:0002460: adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains (Biological process)

"An immune response mediated by lymphocytes expressing specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of germline gene segments encoding immunoglobulin superfamily domains. Recombined receptors for antigen encoded by immunoglobulin superfamily domains include T cell receptors and immunoglobulins (antibodies) produced by B cells. The first encounter with antigen elicits a primary immune response that is slow and not of great magnitude. T and B cells selected by antigen become activated and undergo clonal expansion. A fraction of antigen-reactive T and B cells become memory cells, whereas others differentiate into effector cells. The memory cells generated during the primary response enable a much faster and stronger secondary immune response upon subsequent exposures to the same antigen (immunological memory). An example of this is the adaptive immune response found in Mus musculus." [GOC:add, GOC:mtg_sensu, ISBN:0781735149, ISBN:1405196831]


There are 271 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_823 Solanum tuberosum Agria 100.0 % 0.0 2e-06
Cluster_521 Solanum tuberosum Agria 25.0 % 0.002045 0.01661
Cluster_216 Solanum tuberosum Agria 1.9 % 0.001316 0.010496
Cluster_73 Solanum tuberosum Agria 1.2 % 0.003239 0.011397
Sequences (271) (download table)

InterPro Domains

GO Terms

Family Terms