"The proteolytic cleavages to the Notch protein that occur as a result of ligand binding. Ligand binding at the cell surface exposes an otherwise inaccessible cleavage site in the extracellular portion of Notch, which when cleaved releases a membrane-tethered form of the Notch intracellular domain. Subsequent cleavage within the transmembrane domain then leads to the release of the soluble Notch intracellular domain (NICD)." [GOC:bf, PMID:12651094]
There are 8 sequences with this label.
| Name | Species | % in cluster | p-value | corrected p-value | action |
|---|---|---|---|---|---|
| Cluster_138 | Solanum tuberosum Agria | 1.33 % | 0.001919 | 0.013946 |