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GO:0003918: DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity (Molecular function)

"Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined, driven by ATP hydrolysis. The enzyme changes the linking number in multiples of 2." [PMID:8811192]


There are 175 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Sequences (175) (download table)

InterPro Domains

GO Terms

Family Terms