GO:0060070: canonical Wnt signaling pathway (Biological process)

"The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes." [GOC:bf, GOC:dph, PMID:11532397, PMID:19619488]


There are 52 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Sequences (52) (download table)

InterPro Domains

GO Terms

Family Terms