GO:0097452: GAIT complex (Cellular component)

"A protein complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. The complex binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs and suppresses their translation by blocking the recruitment of the 43S ribosomal complex to m7G cap-bound eIF4G. In humans it includes RPL13A, EPRS, SYNCRIP and GAPDH; mouse complexes lack SYNCRIP." [GOC:br, PMID:15479637, PMID:23071094]


There are 214 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_32 Solanum tuberosum Agria 1.28 % 0.000559 0.00617
Cluster_37 Solanum tuberosum Agria 1.34 % 1.5e-05 0.000145
Sequences (214) (download table)

InterPro Domains

GO Terms

Family Terms