"A protein complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. The complex binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs and suppresses their translation by blocking the recruitment of the 43S ribosomal complex to m7G cap-bound eIF4G. In humans it includes RPL13A, EPRS, SYNCRIP and GAPDH; mouse complexes lack SYNCRIP." [GOC:br, PMID:15479637, PMID:23071094]
There are 214 sequences with this label.
Name | Species | % in cluster | p-value | corrected p-value | action |
---|---|---|---|---|---|
Cluster_32 | Solanum tuberosum Agria | 1.28 % | 0.000559 | 0.00617 | |
Cluster_37 | Solanum tuberosum Agria | 1.34 % | 1.5e-05 | 0.000145 |