GO:0000703: oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity (Molecular function)

"Catalysis of the removal oxidized pyrimidine bases by cleaving the N-C1' glycosidic bond between the oxidized pyrimidine and the deoxyribose sugar. The reaction involves formation of a covalent enzyme-pyrimidine base intermediate. Release of the enzyme and free base by a beta-elimination or a beta, gamma-elimination mechanism results in the cleavage of the DNA backbone 3' of the apyrimidinic (AP) site." [GOC:elh, PMID:11554296]


There are 8 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_757 Solanum tuberosum Agria 50.0 % 0.000102 0.00353
Sequences (8) (download table)

InterPro Domains

GO Terms

Family Terms