"A ubiquitin ligase complex consisting of UBR1 and RAD6 components. It polyubiquitinates proteins containing non-acetylated N-terminal residues causing their subsequent degradation by the proteasome as part of the Ac/N-End Rule pathway. It recognizes non-acetylated N-terminal methionine if it is followed by a hydrophobic residue. Additionally, it acts in an N-end rule independent manner as a component of a novel quality control pathway for proteins synthesized on cytosolic ribosomes." [GOC:bhm, PMID:19531475]
There are 71 sequences with this label.
| Name | Species | % in cluster | p-value | corrected p-value | action |
|---|---|---|---|---|---|
| Cluster_112 | Solanum tuberosum Agria | 1.43 % | 0.010698 | 0.03489 | |
| Cluster_22 | Solanum tuberosum Agria | 1.64 % | 0.000144 | 0.004258 |