"A multiprotein complex that recognizes and ubiquitinates proteins with misfolded luminal and membrane domains during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligase Hrd1p. In mammals, this complex contains the ubiquitin ligase HRD1 (Synoviolin) or AMFR (gp78)." [GOC:bf, GOC:elh, PMID:16619026, PMID:16873066, PMID:21454652]
There are 312 sequences with this label.
Name | Species | % in cluster | p-value | corrected p-value | action |
---|---|---|---|---|---|
Cluster_249 | Solanum tuberosum Agria | 2.2 % | 0.000552 | 0.007849 | |
Cluster_197 | Solanum tuberosum Agria | 0.98 % | 0.002721 | 0.021554 | |
Cluster_81 | Solanum tuberosum Agria | 1.92 % | 0.00072 | 0.005013 |