SOLTUB.AGRIA.G00000005507

Description : Isocitrate dehydrogenase [NAD] subunit, mitochondrial

Gene families : OG_02_0003268 (Orthogroups with 8 Potato genotypes) Phylogenetic Tree(s): No tree available for this family

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR Network (HRR 50 & PCC 0.5): SOLTUB.AGRIA.G00000005507
Cluster	HCCA Clusters (HRR 50 & PCC 0.5): Cluster_51

Target	Alias	Description	ECC score	Gene Family Method
SOLTUB.AGRIA.G00000005625	No alias	Isocitrate dehydrogenase [NAD] subunit, mitochondrial	0.25	Orthogroups with 8 Potato genotypes
SOLTUB.AGRIA.G00000005625	No alias	Isocitrate dehydrogenase [NAD] subunit, mitochondrial	0.25	Orthogroups with 8 Potato genotypes
SOLTUB.AGRIA.G00000005625	No alias	Isocitrate dehydrogenase [NAD] subunit, mitochondrial	0.25	Orthogroups with 8 Potato genotypes

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0000287	magnesium ion binding	IEA	AHRD
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0003862	3-isopropylmalate dehydrogenase activity	IEA	AHRD
MF	GO:0004448	isocitrate dehydrogenase [NAD(P)+] activity	None	Extended
MF	GO:0004449	isocitrate dehydrogenase (NAD+) activity	IEA	AHRD
MF	GO:0005488	binding	None	Extended
MF	GO:0005515	protein binding	IEA	AHRD
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005962	mitochondrial isocitrate dehydrogenase complex (NAD+)	IEA	AHRD
BP	GO:0005975	carbohydrate metabolic process	IEA	AHRD
BP	GO:0006066	alcohol metabolic process	None	Extended
BP	GO:0006082	organic acid metabolic process	None	Extended
BP	GO:0006099	tricarboxylic acid cycle	IEA	AHRD
BP	GO:0006102	isocitrate metabolic process	IEA	AHRD
BP	GO:0006103	2-oxoglutarate metabolic process	IEA	AHRD
BP	GO:0006520	cellular amino acid metabolic process	None	Extended
BP	GO:0006551	leucine metabolic process	None	Extended
BP	GO:0006734	NADH metabolic process	IEA	AHRD
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0008652	cellular amino acid biosynthetic process	None	Extended
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009081	branched-chain amino acid metabolic process	None	Extended
BP	GO:0009082	branched-chain amino acid biosynthetic process	IEA	AHRD
BP	GO:0009098	leucine biosynthetic process	IEA	AHRD
CC	GO:0009507	chloroplast	IEA	AHRD
CC	GO:0009536	plastid	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016053	organic acid biosynthetic process	None	Extended
MF	GO:0016491	oxidoreductase activity	None	Extended
MF	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	None	Extended
MF	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	None	Extended
BP	GO:0019752	carboxylic acid metabolic process	None	Extended
CC	GO:0030062	mitochondrial tricarboxylic acid cycle enzyme complex	None	Extended
CC	GO:0032991	protein-containing complex	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043169	cation binding	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043231	intracellular membrane-bounded organelle	None	Extended
BP	GO:0043436	oxoacid metabolic process	None	Extended
BP	GO:0043648	dicarboxylic acid metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
BP	GO:0044283	small molecule biosynthetic process	None	Extended
CC	GO:0045239	tricarboxylic acid cycle enzyme complex	None	Extended
CC	GO:0045242	isocitrate dehydrogenase complex (NAD+)	None	Extended
BP	GO:0046394	carboxylic acid biosynthetic process	None	Extended
MF	GO:0046872	metal ion binding	None	Extended
MF	GO:0051287	NAD binding	IEA	AHRD
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0072350	tricarboxylic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
CC	GO:0098798	mitochondrial protein-containing complex	None	Extended
CC	GO:0110165	cellular anatomical entity	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901566	organonitrogen compound biosynthetic process	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended
BP	GO:1901605	alpha-amino acid metabolic process	None	Extended
BP	GO:1901607	alpha-amino acid biosynthetic process	None	Extended
BP	GO:1901615	organic hydroxy compound metabolic process	None	Extended
CC	GO:1902494	catalytic complex	None	Extended
BP	GO:1902652	secondary alcohol metabolic process	None	Extended
CC	GO:1990204	oxidoreductase complex	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000082	G1/S transition of mitotic cell cycle	IEP	Predict GO terms from Neighborhoods
MF	GO:0000339	RNA cap binding	IEP	Predict GO terms from Neighborhoods
MF	GO:0000340	RNA 7-methylguanosine cap binding	IEP	Predict GO terms from Neighborhoods
CC	GO:0000932	P-body	IEP	Predict GO terms from Neighborhoods
MF	GO:0001216	DNA-binding transcription activator activity	IEP	Predict GO terms from Neighborhoods
MF	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IEP	Predict GO terms from Neighborhoods
BP	GO:0001662	behavioral fear response	IEP	Predict GO terms from Neighborhoods
BP	GO:0002209	behavioral defense response	IEP	Predict GO terms from Neighborhoods
MF	GO:0003743	translation initiation factor activity	IEP	Predict GO terms from Neighborhoods
MF	GO:0004108	citrate (Si)-synthase activity	IEP	Predict GO terms from Neighborhoods
MF	GO:0004252	serine-type endopeptidase activity	IEP	Predict GO terms from Neighborhoods
MF	GO:0004370	glycerol kinase activity	IEP	Predict GO terms from Neighborhoods
MF	GO:0005524	ATP binding	IEP	Predict GO terms from Neighborhoods
CC	GO:0005845	mRNA cap binding complex	IEP	Predict GO terms from Neighborhoods
BP	GO:0006071	glycerol metabolic process	IEP	Predict GO terms from Neighborhoods
BP	GO:0006072	glycerol-3-phosphate metabolic process	IEP	Predict GO terms from Neighborhoods
BP	GO:0006101	citrate metabolic process	IEP	Predict GO terms from Neighborhoods
BP	GO:0006413	translational initiation	IEP	Predict GO terms from Neighborhoods
BP	GO:0006479	protein methylation	IEP	Predict GO terms from Neighborhoods
BP	GO:0006638	neutral lipid metabolic process	IEP	Predict GO terms from Neighborhoods
BP	GO:0006639	acylglycerol metabolic process	IEP	Predict GO terms from Neighborhoods
BP	GO:0006641	triglyceride metabolic process	IEP	Predict GO terms from Neighborhoods
MF	GO:0008135	translation factor activity, RNA binding	IEP	Predict GO terms from Neighborhoods
BP	GO:0008213	protein alkylation	IEP	Predict GO terms from Neighborhoods
MF	GO:0008236	serine-type peptidase activity	IEP	Predict GO terms from Neighborhoods
MF	GO:0008238	exopeptidase activity	IEP	Predict GO terms from Neighborhoods
MF	GO:0008239	dipeptidyl-peptidase activity	IEP	Predict GO terms from Neighborhoods
MF	GO:0008276	protein methyltransferase activity	IEP	Predict GO terms from Neighborhoods
MF	GO:0008327	methyl-CpG binding	IEP	Predict GO terms from Neighborhoods
BP	GO:0010188	response to microbial phytotoxin	IEP	Predict GO terms from Neighborhoods
MF	GO:0010385	double-stranded methylated DNA binding	IEP	Predict GO terms from Neighborhoods
MF	GO:0010428	methyl-CpNpG binding	IEP	Predict GO terms from Neighborhoods
MF	GO:0010429	methyl-CpNpN binding	IEP	Predict GO terms from Neighborhoods
CC	GO:0010494	cytoplasmic stress granule	IEP	Predict GO terms from Neighborhoods
BP	GO:0010629	negative regulation of gene expression	IEP	Predict GO terms from Neighborhoods
CC	GO:0016281	eukaryotic translation initiation factor 4F complex	IEP	Predict GO terms from Neighborhoods
CC	GO:0016442	RISC complex	IEP	Predict GO terms from Neighborhoods
BP	GO:0016571	histone methylation	IEP	Predict GO terms from Neighborhoods
BP	GO:0017148	negative regulation of translation	IEP	Predict GO terms from Neighborhoods
MF	GO:0017171	serine hydrolase activity	IEP	Predict GO terms from Neighborhoods
BP	GO:0019217	regulation of fatty acid metabolic process	IEP	Predict GO terms from Neighborhoods
BP	GO:0019400	alditol metabolic process	IEP	Predict GO terms from Neighborhoods
BP	GO:0019405	alditol catabolic process	IEP	Predict GO terms from Neighborhoods
BP	GO:0019432	triglyceride biosynthetic process	IEP	Predict GO terms from Neighborhoods
BP	GO:0019563	glycerol catabolic process	IEP	Predict GO terms from Neighborhoods
BP	GO:0019751	polyol metabolic process	IEP	Predict GO terms from Neighborhoods
BP	GO:0030324	lung development	IEP	Predict GO terms from Neighborhoods
BP	GO:0031047	gene silencing by RNA	IEP	Predict GO terms from Neighborhoods
BP	GO:0031048	small non-coding RNA-dependent heterochromatin formation	IEP	Predict GO terms from Neighborhoods
CC	GO:0031332	RNAi effector complex	IEP	Predict GO terms from Neighborhoods
MF	GO:0031369	translation initiation factor binding	IEP	Predict GO terms from Neighborhoods
MF	GO:0031370	eukaryotic initiation factor 4G binding	IEP	Predict GO terms from Neighborhoods
MF	GO:0031490	chromatin DNA binding	IEP	Predict GO terms from Neighborhoods
BP	GO:0031507	heterochromatin formation	IEP	Predict GO terms from Neighborhoods
BP	GO:0031960	response to corticosteroid	IEP	Predict GO terms from Neighborhoods
CC	GO:0033391	chromatoid body	IEP	Predict GO terms from Neighborhoods
BP	GO:0033500	carbohydrate homeostasis	IEP	Predict GO terms from Neighborhoods
BP	GO:0033555	multicellular organismal response to stress	IEP	Predict GO terms from Neighborhoods
BP	GO:0034059	response to anoxia	IEP	Predict GO terms from Neighborhoods
BP	GO:0034249	negative regulation of cellular amide metabolic process	IEP	Predict GO terms from Neighborhoods
CC	GO:0034518	RNA cap binding complex	IEP	Predict GO terms from Neighborhoods
MF	GO:0036440	citrate synthase activity	IEP	Predict GO terms from Neighborhoods
BP	GO:0040029	epigenetic regulation of gene expression	IEP	Predict GO terms from Neighborhoods
MF	GO:0042054	histone methyltransferase activity	IEP	Predict GO terms from Neighborhoods
MF	GO:0042393	histone binding	IEP	Predict GO terms from Neighborhoods
BP	GO:0042593	glucose homeostasis	IEP	Predict GO terms from Neighborhoods
BP	GO:0042596	fear response	IEP	Predict GO terms from Neighborhoods
BP	GO:0044275	cellular carbohydrate catabolic process	IEP	Predict GO terms from Neighborhoods
BP	GO:0044770	cell cycle phase transition	IEP	Predict GO terms from Neighborhoods
BP	GO:0044772	mitotic cell cycle phase transition	IEP	Predict GO terms from Neighborhoods
BP	GO:0044843	cell cycle G1/S phase transition	IEP	Predict GO terms from Neighborhoods
BP	GO:0045017	glycerolipid biosynthetic process	IEP	Predict GO terms from Neighborhoods
MF	GO:0045182	translation regulator activity	IEP	Predict GO terms from Neighborhoods
BP	GO:0045471	response to ethanol	IEP	Predict GO terms from Neighborhoods
BP	GO:0045596	negative regulation of cell differentiation	IEP	Predict GO terms from Neighborhoods
BP	GO:0045664	regulation of neuron differentiation	IEP	Predict GO terms from Neighborhoods
BP	GO:0045665	negative regulation of neuron differentiation	IEP	Predict GO terms from Neighborhoods
BP	GO:0045814	negative regulation of gene expression, epigenetic	IEP	Predict GO terms from Neighborhoods
BP	GO:0045931	positive regulation of mitotic cell cycle	IEP	Predict GO terms from Neighborhoods
BP	GO:0046164	alcohol catabolic process	IEP	Predict GO terms from Neighborhoods
BP	GO:0046167	glycerol-3-phosphate biosynthetic process	IEP	Predict GO terms from Neighborhoods
BP	GO:0046174	polyol catabolic process	IEP	Predict GO terms from Neighborhoods
BP	GO:0046460	neutral lipid biosynthetic process	IEP	Predict GO terms from Neighborhoods
BP	GO:0046463	acylglycerol biosynthetic process	IEP	Predict GO terms from Neighborhoods
MF	GO:0046912	acyltransferase activity, acyl groups converted into alkyl on transfer	IEP	Predict GO terms from Neighborhoods
BP	GO:0048545	response to steroid hormone	IEP	Predict GO terms from Neighborhoods
BP	GO:0050687	negative regulation of defense response to virus	IEP	Predict GO terms from Neighborhoods
BP	GO:0050688	regulation of defense response to virus	IEP	Predict GO terms from Neighborhoods
BP	GO:0050804	modulation of chemical synaptic transmission	IEP	Predict GO terms from Neighborhoods
BP	GO:0051384	response to glucocorticoid	IEP	Predict GO terms from Neighborhoods
BP	GO:0052646	alditol phosphate metabolic process	IEP	Predict GO terms from Neighborhoods
MF	GO:0070012	oligopeptidase activity	IEP	Predict GO terms from Neighborhoods
BP	GO:0070828	heterochromatin organization	IEP	Predict GO terms from Neighborhoods
BP	GO:0071383	cellular response to steroid hormone stimulus	IEP	Predict GO terms from Neighborhoods
BP	GO:0071384	cellular response to corticosteroid stimulus	IEP	Predict GO terms from Neighborhoods
BP	GO:0071385	cellular response to glucocorticoid stimulus	IEP	Predict GO terms from Neighborhoods
BP	GO:0071548	response to dexamethasone	IEP	Predict GO terms from Neighborhoods
BP	GO:0071549	cellular response to dexamethasone stimulus	IEP	Predict GO terms from Neighborhoods
MF	GO:0090079	translation regulator activity, nucleic acid binding	IEP	Predict GO terms from Neighborhoods
CC	GO:0098978	glutamatergic synapse	IEP	Predict GO terms from Neighborhoods
BP	GO:0099170	postsynaptic modulation of chemical synaptic transmission	IEP	Predict GO terms from Neighborhoods
BP	GO:0099177	regulation of trans-synaptic signaling	IEP	Predict GO terms from Neighborhoods
CC	GO:0099522	cytosolic region	IEP	Predict GO terms from Neighborhoods
CC	GO:0099524	postsynaptic cytosol	IEP	Predict GO terms from Neighborhoods
BP	GO:0099547	regulation of translation at synapse, modulating synaptic transmission	IEP	Predict GO terms from Neighborhoods
BP	GO:0099578	regulation of translation at postsynapse, modulating synaptic transmission	IEP	Predict GO terms from Neighborhoods
BP	GO:0140243	regulation of translation at synapse	IEP	Predict GO terms from Neighborhoods
BP	GO:0140245	regulation of translation at postsynapse	IEP	Predict GO terms from Neighborhoods
BP	GO:1901616	organic hydroxy compound catabolic process	IEP	Predict GO terms from Neighborhoods
BP	GO:1901654	response to ketone	IEP	Predict GO terms from Neighborhoods
BP	GO:1901655	cellular response to ketone	IEP	Predict GO terms from Neighborhoods
BP	GO:2000113	negative regulation of cellular macromolecule biosynthetic process	IEP	Predict GO terms from Neighborhoods

InterPro domains	Description	Start	Stop
IPR004434	Isocitrate_DH_NAD	39	367
IPR024084	IsoPropMal-DH-like_dom	40	363

External Links

No external refs found!

SOLTUB.AGRIA.G00000005507

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation