SOLTUB.AGRIA.G00000009931

Description : eukaryotic translation initiation factor 2 (eIF-2) family protein

Gene families : OG_02_0003326 (Orthogroups with 8 Potato genotypes) Phylogenetic Tree(s): No tree available for this family

Sequence : coding (download), protein (download)

Attention: This gene has low abundance.

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR Network (HRR 50 & PCC 0.5): SOLTUB.AGRIA.G00000009931
Cluster	HCCA Clusters (HRR 50 & PCC 0.5): Cluster_10

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	IEA	AHRD
BP	GO:0001732	formation of cytoplasmic translation initiation complex	IEA	AHRD
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003743	translation initiation factor activity	IEA	AHRD
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005515	protein binding	IEA	AHRD
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005829	cytosol	IEA	AHRD
BP	GO:0006417	regulation of translation	None	Extended
BP	GO:0006446	regulation of translational initiation	IEA	AHRD
BP	GO:0006996	organelle organization	None	Extended
MF	GO:0008135	translation factor activity, RNA binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0009889	regulation of biosynthetic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0010468	regulation of gene expression	None	Extended
BP	GO:0010556	regulation of macromolecule biosynthetic process	None	Extended
BP	GO:0010608	post-transcriptional regulation of gene expression	None	Extended
BP	GO:0016043	cellular component organization	None	Extended
MF	GO:0016787	hydrolase activity	IEA	AHRD
BP	GO:0019222	regulation of metabolic process	None	Extended
BP	GO:0022607	cellular component assembly	None	Extended
BP	GO:0022618	ribonucleoprotein complex assembly	None	Extended
BP	GO:0031323	regulation of cellular metabolic process	None	Extended
BP	GO:0031326	regulation of cellular biosynthetic process	None	Extended
CC	GO:0032991	protein-containing complex	None	Extended
CC	GO:0033290	eukaryotic 48S preinitiation complex	IEA	AHRD
BP	GO:0034248	regulation of cellular amide metabolic process	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
BP	GO:0042255	ribosome assembly	None	Extended
BP	GO:0042256	mature ribosome assembly	IEA	AHRD
MF	GO:0043167	ion binding	IEA	AHRD
BP	GO:0043933	protein-containing complex organization	None	Extended
MF	GO:0045182	translation regulator activity	None	Extended
BP	GO:0050789	regulation of biological process	None	Extended
BP	GO:0050794	regulation of cellular process	None	Extended
BP	GO:0051171	regulation of nitrogen compound metabolic process	None	Extended
BP	GO:0051246	regulation of protein metabolic process	None	Extended
BP	GO:0060255	regulation of macromolecule metabolic process	None	Extended
BP	GO:0065003	protein-containing complex assembly	None	Extended
BP	GO:0065007	biological regulation	None	Extended
BP	GO:0070925	organelle assembly	None	Extended
CC	GO:0070993	translation preinitiation complex	None	Extended
BP	GO:0071826	ribonucleoprotein complex subunit organization	None	Extended
BP	GO:0071840	cellular component organization or biogenesis	None	Extended
BP	GO:0080090	regulation of primary metabolic process	None	Extended
MF	GO:0090079	translation regulator activity, nucleic acid binding	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
CC	GO:0110165	cellular anatomical entity	None	Extended
BP	GO:0140694	non-membrane-bounded organelle assembly	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
CC	GO:1990904	ribonucleoprotein complex	None	Extended
BP	GO:2000112	regulation of cellular macromolecule biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000070	mitotic sister chromatid segregation	IEP	Predict GO terms from Neighborhoods
CC	GO:0000243	commitment complex	IEP	Predict GO terms from Neighborhoods
BP	GO:0000375	RNA splicing, via transesterification reactions	IEP	Predict GO terms from Neighborhoods
BP	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile	IEP	Predict GO terms from Neighborhoods
BP	GO:0000381	regulation of alternative mRNA splicing, via spliceosome	IEP	Predict GO terms from Neighborhoods
BP	GO:0000398	mRNA splicing, via spliceosome	IEP	Predict GO terms from Neighborhoods
BP	GO:0000451	rRNA 2'-O-methylation	IEP	Predict GO terms from Neighborhoods
BP	GO:0000494	box C/D RNA 3'-end processing	IEP	Predict GO terms from Neighborhoods
BP	GO:0000819	sister chromatid segregation	IEP	Predict GO terms from Neighborhoods
MF	GO:0001056	RNA polymerase III activity	IEP	Predict GO terms from Neighborhoods
MF	GO:0001091	RNA polymerase II general transcription initiation factor binding	IEP	Predict GO terms from Neighborhoods
MF	GO:0001094	TFIID-class transcription factor complex binding	IEP	Predict GO terms from Neighborhoods
MF	GO:0001223	transcription coactivator binding	IEP	Predict GO terms from Neighborhoods
BP	GO:0001501	skeletal system development	IEP	Predict GO terms from Neighborhoods
CC	GO:0001651	dense fibrillar component	IEP	Predict GO terms from Neighborhoods
CC	GO:0001652	granular component	IEP	Predict GO terms from Neighborhoods
BP	GO:0001831	trophectodermal cellular morphogenesis	IEP	Predict GO terms from Neighborhoods
MF	GO:0001882	nucleoside binding	IEP	Predict GO terms from Neighborhoods
BP	GO:0002181	cytoplasmic translation	IEP	Predict GO terms from Neighborhoods
BP	GO:0002761	regulation of myeloid leukocyte differentiation	IEP	Predict GO terms from Neighborhoods
BP	GO:0002762	negative regulation of myeloid leukocyte differentiation	IEP	Predict GO terms from Neighborhoods
BP	GO:0003360	brainstem development	IEP	Predict GO terms from Neighborhoods
MF	GO:0003723	RNA binding	IEP	Predict GO terms from Neighborhoods
MF	GO:0003729	mRNA binding	IEP	Predict GO terms from Neighborhoods
MF	GO:0003735	structural constituent of ribosome	IEP	Predict GO terms from Neighborhoods
MF	GO:0004363	glutathione synthase activity	IEP	Predict GO terms from Neighborhoods
MF	GO:0005112	Notch binding	IEP	Predict GO terms from Neighborhoods
MF	GO:0005198	structural molecule activity	IEP	Predict GO terms from Neighborhoods
CC	GO:0005654	nucleoplasm	IEP	Predict GO terms from Neighborhoods
CC	GO:0005666	RNA polymerase III complex	IEP	Predict GO terms from Neighborhoods
CC	GO:0005681	spliceosomal complex	IEP	Predict GO terms from Neighborhoods
CC	GO:0005684	U2-type spliceosomal complex	IEP	Predict GO terms from Neighborhoods
CC	GO:0005736	RNA polymerase I complex	IEP	Predict GO terms from Neighborhoods
CC	GO:0005791	rough endoplasmic reticulum	IEP	Predict GO terms from Neighborhoods
CC	GO:0005827	polar microtubule	IEP	Predict GO terms from Neighborhoods
BP	GO:0006360	transcription by RNA polymerase I	IEP	Predict GO terms from Neighborhoods
BP	GO:0006383	transcription by RNA polymerase III	IEP	Predict GO terms from Neighborhoods
BP	GO:0006386	termination of RNA polymerase III transcription	IEP	Predict GO terms from Neighborhoods
BP	GO:0006412	translation	IEP	Predict GO terms from Neighborhoods
BP	GO:0006515	protein quality control for misfolded or incompletely synthesized proteins	IEP	Predict GO terms from Neighborhoods
BP	GO:0006518	peptide metabolic process	IEP	Predict GO terms from Neighborhoods
BP	GO:0006750	glutathione biosynthetic process	IEP	Predict GO terms from Neighborhoods
BP	GO:0006901	vesicle coating	IEP	Predict GO terms from Neighborhoods
BP	GO:0007000	nucleolus organization	IEP	Predict GO terms from Neighborhoods
BP	GO:0007229	integrin-mediated signaling pathway	IEP	Predict GO terms from Neighborhoods
BP	GO:0007498	mesoderm development	IEP	Predict GO terms from Neighborhoods
MF	GO:0008097	5S rRNA binding	IEP	Predict GO terms from Neighborhoods
MF	GO:0008649	rRNA methyltransferase activity	IEP	Predict GO terms from Neighborhoods
BP	GO:0009059	macromolecule biosynthetic process	IEP	Predict GO terms from Neighborhoods
BP	GO:0009304	tRNA transcription	IEP	Predict GO terms from Neighborhoods
BP	GO:0010390	histone monoubiquitination	IEP	Predict GO terms from Neighborhoods
BP	GO:0010628	positive regulation of gene expression	IEP	Predict GO terms from Neighborhoods
CC	GO:0014069	postsynaptic density	IEP	Predict GO terms from Neighborhoods
CC	GO:0015934	large ribosomal subunit	IEP	Predict GO terms from Neighborhoods
BP	GO:0016055	Wnt signaling pathway	IEP	Predict GO terms from Neighborhoods
MF	GO:0016420	malonyltransferase activity	IEP	Predict GO terms from Neighborhoods
CC	GO:0016469	proton-transporting two-sector ATPase complex	IEP	Predict GO terms from Neighborhoods
BP	GO:0017126	nucleologenesis	IEP	Predict GO terms from Neighborhoods
BP	GO:0018364	peptidyl-glutamine methylation	IEP	Predict GO terms from Neighborhoods
BP	GO:0019184	nonribosomal peptide biosynthetic process	IEP	Predict GO terms from Neighborhoods
MF	GO:0019843	rRNA binding	IEP	Predict GO terms from Neighborhoods
BP	GO:0019985	translesion synthesis	IEP	Predict GO terms from Neighborhoods
BP	GO:0021987	cerebral cortex development	IEP	Predict GO terms from Neighborhoods
BP	GO:0022612	gland morphogenesis	IEP	Predict GO terms from Neighborhoods
CC	GO:0022625	cytosolic large ribosomal subunit	IEP	Predict GO terms from Neighborhoods
BP	GO:0030330	DNA damage response, signal transduction by p53 class mediator	IEP	Predict GO terms from Neighborhoods
MF	GO:0030628	pre-mRNA 3'-splice site binding	IEP	Predict GO terms from Neighborhoods
BP	GO:0030852	regulation of granulocyte differentiation	IEP	Predict GO terms from Neighborhoods
BP	GO:0030853	negative regulation of granulocyte differentiation	IEP	Predict GO terms from Neighborhoods
CC	GO:0031011	Ino80 complex	IEP	Predict GO terms from Neighborhoods
BP	GO:0031126	sno(s)RNA 3'-end processing	IEP	Predict GO terms from Neighborhoods
BP	GO:0031145	anaphase-promoting complex-dependent catabolic process	IEP	Predict GO terms from Neighborhoods
BP	GO:0031167	rRNA methylation	IEP	Predict GO terms from Neighborhoods
MF	GO:0031208	POZ domain binding	IEP	Predict GO terms from Neighborhoods
BP	GO:0031396	regulation of protein ubiquitination	IEP	Predict GO terms from Neighborhoods
CC	GO:0031428	box C/D RNP complex	IEP	Predict GO terms from Neighborhoods
CC	GO:0031463	Cul3-RING ubiquitin ligase complex	IEP	Predict GO terms from Neighborhoods
CC	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex	IEP	Predict GO terms from Neighborhoods
CC	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex	IEP	Predict GO terms from Neighborhoods
CC	GO:0031672	A band	IEP	Predict GO terms from Neighborhoods
MF	GO:0032549	ribonucleoside binding	IEP	Predict GO terms from Neighborhoods
BP	GO:0032648	regulation of interferon-beta production	IEP	Predict GO terms from Neighborhoods
BP	GO:0032728	positive regulation of interferon-beta production	IEP	Predict GO terms from Neighborhoods
BP	GO:0032986	protein-DNA complex disassembly	IEP	Predict GO terms from Neighborhoods
CC	GO:0033176	proton-transporting V-type ATPase complex	IEP	Predict GO terms from Neighborhoods
CC	GO:0033291	eukaryotic 80S initiation complex	IEP	Predict GO terms from Neighborhoods
BP	GO:0033522	histone H2A ubiquitination	IEP	Predict GO terms from Neighborhoods
MF	GO:0033810	anthocyanin 5-O-glucoside 6'''-O-malonyltransferase activity	IEP	Predict GO terms from Neighborhoods
BP	GO:0033967	box C/D RNA metabolic process	IEP	Predict GO terms from Neighborhoods
BP	GO:0034463	90S preribosome assembly	IEP	Predict GO terms from Neighborhoods
BP	GO:0034517	ribophagy	IEP	Predict GO terms from Neighborhoods
BP	GO:0034645	cellular macromolecule biosynthetic process	IEP	Predict GO terms from Neighborhoods
BP	GO:0034963	box C/D RNA processing	IEP	Predict GO terms from Neighborhoods
BP	GO:0035019	somatic stem cell population maintenance	IEP	Predict GO terms from Neighborhoods
BP	GO:0035023	regulation of Rho protein signal transduction	IEP	Predict GO terms from Neighborhoods
BP	GO:0035024	negative regulation of Rho protein signal transduction	IEP	Predict GO terms from Neighborhoods
BP	GO:0035518	histone H2A monoubiquitination	IEP	Predict GO terms from Neighborhoods
MF	GO:0036009	protein-glutamine N-methyltransferase activity	IEP	Predict GO terms from Neighborhoods
CC	GO:0036126	sperm flagellum	IEP	Predict GO terms from Neighborhoods
BP	GO:0040016	embryonic cleavage	IEP	Predict GO terms from Neighborhoods
BP	GO:0042474	middle ear morphogenesis	IEP	Predict GO terms from Neighborhoods
MF	GO:0042625	ATPase-coupled ion transmembrane transporter activity	IEP	Predict GO terms from Neighborhoods
BP	GO:0042752	regulation of circadian rhythm	IEP	Predict GO terms from Neighborhoods
CC	GO:0042788	polysomal ribosome	IEP	Predict GO terms from Neighborhoods
BP	GO:0042797	tRNA transcription by RNA polymerase III	IEP	Predict GO terms from Neighborhoods
BP	GO:0043043	peptide biosynthetic process	IEP	Predict GO terms from Neighborhoods
BP	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling	IEP	Predict GO terms from Neighborhoods
CC	GO:0043228	non-membrane-bounded organelle	IEP	Predict GO terms from Neighborhoods
CC	GO:0043232	intracellular non-membrane-bounded organelle	IEP	Predict GO terms from Neighborhoods
BP	GO:0043484	regulation of RNA splicing	IEP	Predict GO terms from Neighborhoods
BP	GO:0043604	amide biosynthetic process	IEP	Predict GO terms from Neighborhoods
BP	GO:0044346	fibroblast apoptotic process	IEP	Predict GO terms from Neighborhoods
CC	GO:0044391	ribosomal subunit	IEP	Predict GO terms from Neighborhoods
MF	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	IEP	Predict GO terms from Neighborhoods
BP	GO:0045053	protein retention in Golgi apparatus	IEP	Predict GO terms from Neighborhoods
CC	GO:0045111	intermediate filament cytoskeleton	IEP	Predict GO terms from Neighborhoods
BP	GO:0045292	mRNA cis splicing, via spliceosome	IEP	Predict GO terms from Neighborhoods
BP	GO:0045638	negative regulation of myeloid cell differentiation	IEP	Predict GO terms from Neighborhoods
BP	GO:0045861	negative regulation of proteolysis	IEP	Predict GO terms from Neighborhoods
BP	GO:0046580	negative regulation of Ras protein signal transduction	IEP	Predict GO terms from Neighborhoods
MF	GO:0046961	proton-transporting ATPase activity, rotational mechanism	IEP	Predict GO terms from Neighborhoods
MF	GO:0047165	flavonol-3-O-beta-glucoside O-malonyltransferase activity	IEP	Predict GO terms from Neighborhoods
BP	GO:0048024	regulation of mRNA splicing, via spliceosome	IEP	Predict GO terms from Neighborhoods
BP	GO:0048208	COPII vesicle coating	IEP	Predict GO terms from Neighborhoods
BP	GO:0048254	snoRNA localization	IEP	Predict GO terms from Neighborhoods
BP	GO:0048318	axial mesoderm development	IEP	Predict GO terms from Neighborhoods
BP	GO:0050684	regulation of mRNA processing	IEP	Predict GO terms from Neighborhoods
MF	GO:0050733	RS domain binding	IEP	Predict GO terms from Neighborhoods
MF	GO:0050736	O-malonyltransferase activity	IEP	Predict GO terms from Neighborhoods
BP	GO:0051058	negative regulation of small GTPase mediated signal transduction	IEP	Predict GO terms from Neighborhoods
BP	GO:0051444	negative regulation of ubiquitin-protein transferase activity	IEP	Predict GO terms from Neighborhoods
MF	GO:0055105	ubiquitin-protein transferase inhibitor activity	IEP	Predict GO terms from Neighborhoods
BP	GO:0060628	regulation of ER to Golgi vesicle-mediated transport	IEP	Predict GO terms from Neighborhoods
MF	GO:0070180	large ribosomal subunit rRNA binding	IEP	Predict GO terms from Neighborhoods
BP	GO:0070453	regulation of heme biosynthetic process	IEP	Predict GO terms from Neighborhoods
BP	GO:0070914	UV-damage excision repair	IEP	Predict GO terms from Neighborhoods
CC	GO:0070992	translation initiation complex	IEP	Predict GO terms from Neighborhoods
CC	GO:0071004	U2-type prespliceosome	IEP	Predict GO terms from Neighborhoods
CC	GO:0071010	prespliceosome	IEP	Predict GO terms from Neighborhoods
CC	GO:0071013	catalytic step 2 spliceosome	IEP	Predict GO terms from Neighborhoods
BP	GO:0071347	cellular response to interleukin-1	IEP	Predict GO terms from Neighborhoods
BP	GO:0071630	nuclear protein quality control by the ubiquitin-proteasome system	IEP	Predict GO terms from Neighborhoods
BP	GO:0072576	liver morphogenesis	IEP	Predict GO terms from Neighborhoods
BP	GO:0072716	response to actinomycin D	IEP	Predict GO terms from Neighborhoods
BP	GO:0072717	cellular response to actinomycin D	IEP	Predict GO terms from Neighborhoods
CC	GO:0089701	U2AF complex	IEP	Predict GO terms from Neighborhoods
CC	GO:0097346	INO80-type complex	IEP	Predict GO terms from Neighborhoods
CC	GO:0097729	9+2 motile cilium	IEP	Predict GO terms from Neighborhoods
CC	GO:0099572	postsynaptic specialization	IEP	Predict GO terms from Neighborhoods
MF	GO:0140102	catalytic activity, acting on a rRNA	IEP	Predict GO terms from Neighborhoods
CC	GO:0140513	nuclear protein-containing complex	IEP	Predict GO terms from Neighborhoods
BP	GO:1902106	negative regulation of leukocyte differentiation	IEP	Predict GO terms from Neighborhoods
BP	GO:1903311	regulation of mRNA metabolic process	IEP	Predict GO terms from Neighborhoods
BP	GO:1903320	regulation of protein modification by small protein conjugation or removal	IEP	Predict GO terms from Neighborhoods
BP	GO:1903707	negative regulation of hemopoiesis	IEP	Predict GO terms from Neighborhoods
MF	GO:1904091	non-ribosomal peptide synthetase activity	IEP	Predict GO terms from Neighborhoods
BP	GO:1904526	regulation of microtubule binding	IEP	Predict GO terms from Neighborhoods
BP	GO:1904667	negative regulation of ubiquitin protein ligase activity	IEP	Predict GO terms from Neighborhoods
BP	GO:1905114	cell surface receptor signaling pathway involved in cell-cell signaling	IEP	Predict GO terms from Neighborhoods
BP	GO:1990258	histone glutamine methylation	IEP	Predict GO terms from Neighborhoods
MF	GO:1990259	histone-glutamine methyltransferase activity	IEP	Predict GO terms from Neighborhoods
BP	GO:1990416	cellular response to brain-derived neurotrophic factor stimulus	IEP	Predict GO terms from Neighborhoods
CC	GO:1990861	Ubp3-Bre5 deubiquitination complex	IEP	Predict GO terms from Neighborhoods
MF	GO:1990935	splicing factor binding	IEP	Predict GO terms from Neighborhoods
MF	GO:1990948	ubiquitin ligase inhibitor activity	IEP	Predict GO terms from Neighborhoods
BP	GO:2000001	regulation of DNA damage checkpoint	IEP	Predict GO terms from Neighborhoods
BP	GO:2000819	regulation of nucleotide-excision repair	IEP	Predict GO terms from Neighborhoods

InterPro domains	Description	Start	Stop
IPR036925	TIF_IF2_dom3_sf	96	183
IPR023115	TIF_IF2_dom3	109	182

External Links

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SOLTUB.AGRIA.G00000009931

Expression Profile

Co-expression Networks

Functional Annotation