GO:0016236: macroautophagy (Biological process)

"The major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane-bounded autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane-bounded structure. Autophagosomes then fuse with a lysosome (or vacuole) releasing single-membrane-bounded autophagic bodies that are then degraded within the lysosome (or vacuole). Some types of macroautophagy, e.g. pexophagy, mitophagy, involve selective targeting of the targets to be degraded." [PMID:11099404, PMID:12914914, PMID:15798367, PMID:16973210, PMID:20159618, PMID:9412464]


There are 848 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_230 Solanum tuberosum Agria 1.83 % 0.00871 0.035702
Cluster_823 Solanum tuberosum Agria 100.0 % 6e-06 2.3e-05
Cluster_83 Solanum tuberosum Agria 2.52 % 0.000763 0.005055
Cluster_394 Solanum tuberosum Agria 33.33 % 0.007656 0.020591
Cluster_763 Solanum tuberosum Agria 100.0 % 6e-06 6.9e-05
Cluster_128 Solanum tuberosum Agria 3.06 % 0.002072 0.025759
Cluster_521 Solanum tuberosum Agria 25.0 % 0.010195 0.035011
Cluster_37 Solanum tuberosum Agria 2.23 % 0.000286 0.002052
Cluster_172 Solanum tuberosum Agria 3.08 % 0.012137 0.036182
Cluster_217 Solanum tuberosum Agria 3.61 % 0.001287 0.014657
Sequences (848) (download table)

Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro Domains

Family Terms