GO:0017054: negative cofactor 2 complex (Cellular component)

"A heterodimeric protein complex that can stably associate with TATA-binding protein on promoters, thereby preventing the assembly of transcription factors TFIIA and TFIIB and leading to repression of RNA polymerase II transcription. The two subunits, NC2alpha (Drap1) and NC2beta (Dr1), dimerize through histone fold domains of the H2A/H2B type present in the amino termini." [PMID:15574413]


There are 52 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_209 Solanum tuberosum Agria 2.08 % 0.006125 0.049177
Sequences (52) (download table)

InterPro Domains

GO Terms

Family Terms