GO:0043223: cytoplasmic SCF ubiquitin ligase complex (Cellular component)

"A ubiquitin ligase complex, located in the cytoplasm, in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1)." [PMID:15571813, PMID:15688063]


There are 243 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_112 Solanum tuberosum Agria 2.86 % 0.00116 0.006486
Cluster_52 Solanum tuberosum Agria 1.05 % 0.008259 0.046173
Sequences (243) (download table)

InterPro Domains

GO Terms

Family Terms