"A transcription coregulator activity that activates or increases the transcription of specific gene sets via binding to a DNA-bound DNA-binding transcription factor, either on its own or as part of a complex. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coactivators modifies chromatin structure through covalent modification of histones. A second class remodels the conformation of chromatin in an ATP-dependent fashion. A third class modulates interactions of DNA-bound DNA-binding transcription factors with other transcription coregulators. A fourth class of coactivator activity is the bridging of a DNA-binding transcription factor to the general (basal) transcription machinery. The Mediator complex, which bridges sequence-specific DNA binding transcription factors and RNA polymerase, is also a transcription coactivator." [GOC:txnOH-2018, PMID:10213677, PMID:16858867]
There are 1213 sequences with this label.
| Name | Species | % in cluster | p-value | corrected p-value | action |
|---|---|---|---|---|---|
| Cluster_124 | Solanum tuberosum Agria | 2.58 % | 0.003396 | 0.031526 | |
| Cluster_628 | Solanum tuberosum Agria | 50.0 % | 0.010258 | 0.037019 | |
| Cluster_780 | Solanum tuberosum Agria | 50.0 % | 0.010258 | 0.039687 | |
| Cluster_83 | Solanum tuberosum Agria | 4.4 % | 2e-05 | 0.000257 | |
| Cluster_22 | Solanum tuberosum Agria | 4.1 % | 0.000436 | 0.009937 | |
| Cluster_818 | Solanum tuberosum Agria | 33.33 % | 0.015348 | 0.03548 | |
| Cluster_36 | Solanum tuberosum Agria | 2.16 % | 0.007046 | 0.032607 | |
| Cluster_210 | Solanum tuberosum Agria | 6.52 % | 8e-06 | 0.00134 | |
| Cluster_134 | Solanum tuberosum Agria | 5.33 % | 0.00062 | 0.007705 | |
| Cluster_264 | Solanum tuberosum Agria | 3.42 % | 0.0032 | 0.037418 | |
| Cluster_243 | Solanum tuberosum Agria | 5.66 % | 0.002597 | 0.014975 |