GO:0003714: transcription corepressor activity (Molecular function)

"A transcription coregulator activity that represses or decreases the transcription of specific gene sets via binding to a DNA-bound DNA-binding transcription factor, either on its own or as part of a complex. Corepressors often act by altering chromatin structure and modifications. For example, one class of transcription corepressors modifies chromatin structure through covalent modification of histones. A second class remodels the conformation of chromatin in an ATP-dependent fashion. A third class modulates interactions of DNA-bound DNA-binding transcription factors with other transcription coregulators." [GOC:txnOH-2018, PMID:10213677, PMID:16858867]


There are 1063 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_107 Solanum tuberosum Agria 8.54 % 0.0 2e-06
Cluster_823 Solanum tuberosum Agria 100.0 % 1.5e-05 4.5e-05
Cluster_780 Solanum tuberosum Agria 50.0 % 0.007711 0.033089
Cluster_83 Solanum tuberosum Agria 3.77 % 3.8e-05 0.000432
Cluster_72 Solanum tuberosum Agria 3.6 % 0.00093 0.010018
Cluster_36 Solanum tuberosum Agria 2.16 % 0.0021 0.014021
Cluster_17 Solanum tuberosum Agria 3.31 % 0.001281 0.013762
Cluster_521 Solanum tuberosum Agria 25.0 % 0.015364 0.043554
Sequences (1063) (download table)

Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro Domains

Family Terms