GO:0051880: G-quadruplex DNA binding (Molecular function)

"Binding to G-quadruplex DNA structures, in which groups of four guanines adopt a flat, cyclic Hoogsteen hydrogen-bonding arrangement known as a guanine tetrad. The stacking of guanine tetrads results in G-quadruplex DNA structures. G-quadruplex DNA can form under physiological conditions from some G-rich sequences, such as those found in telomeres, immunoglobulin switch regions, gene promoters, fragile X repeats, and the dimerization domain in the human immunodeficiency virus (HIV) genome." [PMID:16142245, PMID:9512530]


There are 467 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_534 Solanum tuberosum Agria 100.0 % 1e-06 3e-06
Cluster_325 Solanum tuberosum Agria 33.33 % 0.002454 0.010567
Sequences (467) (download table)

Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro Domains

Family Terms