Coexpression cluster: Cluster_325 (HCCA Clusters (HRR 50 & PCC 0.5))

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Average Expression Profile

Enriched GO Terms (corrected p-value < 0.05) (download table)
ID Label % in cluster Enrichment log2 p-value Corrected p-value
GO:0043138 3'-5' DNA helicase activity 66.67% (2/3) 9.72 2e-06 0.000668
GO:0017116 single-stranded DNA helicase activity 66.67% (2/3) 9.21 4e-06 0.000679
GO:0000725 recombinational repair 66.67% (2/3) 7.48 4.1e-05 0.001686
GO:0000724 double-strand break repair via homologous recombination 66.67% (2/3) 7.5 4e-05 0.001845
GO:0003678 DNA helicase activity 66.67% (2/3) 7.55 3.8e-05 0.001965
GO:0032993 protein-DNA complex 66.67% (2/3) 7.29 5.4e-05 0.001987
GO:0071103 DNA conformation change 66.67% (2/3) 7.59 3.5e-05 0.002162
GO:0000781 chromosome, telomeric region 66.67% (2/3) 7.67 3.2e-05 0.002332
GO:0032392 DNA geometric change 66.67% (2/3) 7.79 2.7e-05 0.002476
GO:0032508 DNA duplex unwinding 66.67% (2/3) 7.98 2.1e-05 0.002512
GO:0008094 ATP-dependent activity, acting on DNA 66.67% (2/3) 6.87 9.7e-05 0.002954
GO:0003697 single-stranded DNA binding 66.67% (2/3) 6.91 9.2e-05 0.003051
GO:0006302 double-strand break repair 66.67% (2/3) 6.77 0.000111 0.003132
GO:0006310 DNA recombination 66.67% (2/3) 6.66 0.000129 0.003363
GO:0004386 helicase activity 66.67% (2/3) 6.51 0.000158 0.003618
GO:0098687 chromosomal region 66.67% (2/3) 6.52 0.000157 0.003832
GO:0032406 MutLbeta complex binding 33.33% (1/3) 12.08 0.00023 0.004213
GO:0032408 MutSbeta complex binding 33.33% (1/3) 12.08 0.00023 0.004213
GO:0036298 recombinational interstrand cross-link repair 33.33% (1/3) 12.08 0.00023 0.004213
GO:0097362 MCM8-MCM9 complex 33.33% (1/3) 12.08 0.00023 0.004213
GO:0140097 catalytic activity, acting on DNA 66.67% (2/3) 6.19 0.000249 0.004347
GO:0051097 negative regulation of helicase activity 33.33% (1/3) 11.35 0.000384 0.006106
GO:0070716 mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication 33.33% (1/3) 11.35 0.000384 0.006106
GO:0007534 gene conversion at mating-type locus 33.33% (1/3) 10.5 0.000691 0.006652
GO:0031860 telomeric 3' overhang formation 33.33% (1/3) 10.5 0.000691 0.006652
GO:0071139 resolution of recombination intermediates 33.33% (1/3) 10.5 0.000691 0.006652
GO:0072757 cellular response to camptothecin 33.33% (1/3) 10.5 0.000691 0.006652
GO:1901291 negative regulation of double-strand break repair via single-strand annealing 33.33% (1/3) 10.5 0.000691 0.006652
GO:0000403 Y-form DNA binding 33.33% (1/3) 10.21 0.000844 0.006716
GO:0061820 telomeric D-loop disassembly 33.33% (1/3) 10.21 0.000844 0.006716
GO:0090657 telomeric loop disassembly 33.33% (1/3) 10.21 0.000844 0.006716
GO:1901563 response to camptothecin 33.33% (1/3) 10.21 0.000844 0.006716
GO:0010946 regulation of meiotic joint molecule formation 33.33% (1/3) 11.08 0.00046 0.006741
GO:0010947 negative regulation of meiotic joint molecule formation 33.33% (1/3) 11.08 0.00046 0.006741
GO:0010705 meiotic DNA double-strand break processing involved in reciprocal meiotic recombination 33.33% (1/3) 10.67 0.000614 0.006809
GO:0043590 bacterial nucleoid 33.33% (1/3) 10.67 0.000614 0.006809
GO:0061749 forked DNA-dependent helicase activity 33.33% (1/3) 10.67 0.000614 0.006809
GO:0061821 telomeric D-loop binding 33.33% (1/3) 10.67 0.000614 0.006809
GO:0062037 D-loop DNA binding 33.33% (1/3) 10.67 0.000614 0.006809
GO:1905773 8-hydroxy-2'-deoxyguanosine DNA binding 33.33% (1/3) 10.67 0.000614 0.006809
GO:0042555 MCM complex 33.33% (1/3) 10.35 0.000767 0.00685
GO:0000405 bubble DNA binding 33.33% (1/3) 10.35 0.000767 0.00685
GO:0000706 meiotic DNA double-strand break processing 33.33% (1/3) 10.35 0.000767 0.00685
GO:0033260 nuclear DNA replication 33.33% (1/3) 10.08 0.000921 0.006877
GO:0000732 strand displacement 33.33% (1/3) 10.08 0.000921 0.006877
GO:0017117 single-stranded DNA-dependent ATP-dependent DNA helicase complex 33.33% (1/3) 10.08 0.000921 0.006877
GO:0051095 regulation of helicase activity 33.33% (1/3) 9.86 0.001074 0.006897
GO:0030894 replisome 33.33% (1/3) 9.86 0.001074 0.006897
GO:0032357 oxidized purine DNA binding 33.33% (1/3) 9.86 0.001074 0.006897
GO:0035822 gene conversion 33.33% (1/3) 9.86 0.001074 0.006897
GO:0071312 cellular response to alkaloid 33.33% (1/3) 9.86 0.001074 0.006897
GO:0051276 chromosome organization 66.67% (2/3) 5.69 0.000494 0.006947
GO:0000800 lateral element 33.33% (1/3) 9.76 0.001151 0.00702
GO:0032356 oxidized DNA binding 33.33% (1/3) 9.76 0.001151 0.00702
GO:0072711 cellular response to hydroxyurea 33.33% (1/3) 9.76 0.001151 0.00702
GO:0032404 mismatch repair complex binding 33.33% (1/3) 9.97 0.000997 0.00702
GO:0031573 mitotic intra-S DNA damage checkpoint signaling 33.33% (1/3) 9.97 0.000997 0.00702
GO:0033202 DNA helicase complex 33.33% (1/3) 9.97 0.000997 0.00702
GO:0006281 DNA repair 66.67% (2/3) 5.31 0.000834 0.00727
GO:0032407 MutSalpha complex binding 33.33% (1/3) 10.86 0.000537 0.007282
GO:0031261 DNA replication preinitiation complex 33.33% (1/3) 9.67 0.001228 0.007365
GO:0045003 double-strand break repair via synthesis-dependent strand annealing 33.33% (1/3) 9.58 0.001304 0.007577
GO:0072710 response to hydroxyurea 33.33% (1/3) 9.58 0.001304 0.007577
GO:0140657 ATP-dependent activity 66.67% (2/3) 4.92 0.001423 0.008136
GO:1990918 double-strand break repair involved in meiotic recombination 33.33% (1/3) 9.42 0.001458 0.008207
GO:0009378 four-way junction helicase activity 33.33% (1/3) 9.35 0.001534 0.008508
GO:0000712 resolution of meiotic recombination intermediates 33.33% (1/3) 9.28 0.001611 0.0088
GO:0006974 cellular response to DNA damage stimulus 66.67% (2/3) 4.81 0.001659 0.008929
GO:0006270 DNA replication initiation 33.33% (1/3) 9.21 0.001688 0.008952
GO:0000400 four-way junction DNA binding 33.33% (1/3) 9.15 0.001764 0.009225
GO:0044806 G-quadruplex DNA unwinding 33.33% (1/3) 9.08 0.001841 0.009358
GO:2000780 negative regulation of double-strand break repair 33.33% (1/3) 9.08 0.001841 0.009358
GO:0036310 ATP-dependent DNA/DNA annealing activity 33.33% (1/3) 9.03 0.001918 0.009614
GO:0140640 catalytic activity, acting on a nucleic acid 66.67% (2/3) 4.68 0.001982 0.009803
GO:0000722 telomere maintenance via recombination 33.33% (1/3) 8.86 0.002148 0.009949
GO:0007095 mitotic G2 DNA damage checkpoint signaling 33.33% (1/3) 8.86 0.002148 0.009949
GO:1990814 DNA/DNA annealing activity 33.33% (1/3) 8.86 0.002148 0.009949
GO:0000729 DNA double-strand break processing 33.33% (1/3) 8.91 0.002071 0.009973
GO:0045738 negative regulation of DNA repair 33.33% (1/3) 8.91 0.002071 0.009973
GO:0032780 negative regulation of ATP-dependent activity 33.33% (1/3) 8.72 0.002377 0.010359
GO:0071168 protein localization to chromatin 33.33% (1/3) 8.72 0.002377 0.010359
GO:0022616 DNA strand elongation 33.33% (1/3) 8.72 0.002377 0.010359
GO:0010520 regulation of reciprocal meiotic recombination 33.33% (1/3) 8.76 0.002301 0.010396
GO:0006259 DNA metabolic process 66.67% (2/3) 4.58 0.002292 0.010484
GO:0051880 G-quadruplex DNA binding 33.33% (1/3) 8.67 0.002454 0.010567
GO:0140666 annealing activity 33.33% (1/3) 8.63 0.002531 0.01077
GO:0036297 interstrand cross-link repair 33.33% (1/3) 8.58 0.002607 0.010969
GO:0006312 mitotic recombination 33.33% (1/3) 8.46 0.002837 0.0118
GO:0031297 replication fork processing 33.33% (1/3) 8.35 0.003067 0.012612
GO:0050790 regulation of catalytic activity 66.67% (2/3) 4.33 0.003208 0.013046
GO:0006268 DNA unwinding involved in DNA replication 33.33% (1/3) 8.24 0.003297 0.013115
GO:0010165 response to X-ray 33.33% (1/3) 8.24 0.003297 0.013115
GO:0065003 protein-containing complex assembly 66.67% (2/3) 4.26 0.00355 0.013678
GO:0000731 DNA synthesis involved in DNA repair 33.33% (1/3) 8.15 0.003526 0.013731
GO:0006303 double-strand break repair via nonhomologous end joining 33.33% (1/3) 8.15 0.003526 0.013731
GO:0044818 mitotic G2/M transition checkpoint 33.33% (1/3) 8.08 0.00368 0.014028
GO:0006298 mismatch repair 33.33% (1/3) 8.05 0.003756 0.014173
GO:0140513 nuclear protein-containing complex 66.67% (2/3) 4.13 0.004229 0.015794
GO:0022402 cell cycle process 66.67% (2/3) 4.12 0.00428 0.015822
GO:0035825 homologous recombination 33.33% (1/3) 7.79 0.004522 0.016549
GO:0043933 protein-containing complex organization 66.67% (2/3) 4.06 0.004672 0.016931
GO:0045005 DNA-templated DNA replication maintenance of fidelity 33.33% (1/3) 7.69 0.004828 0.017154
GO:0051782 negative regulation of cell division 33.33% (1/3) 7.69 0.004828 0.017154
GO:0016605 PML body 33.33% (1/3) 7.65 0.004981 0.017528
GO:0034502 protein localization to chromosome 33.33% (1/3) 7.58 0.00521 0.017656
GO:0045910 negative regulation of DNA recombination 33.33% (1/3) 7.58 0.00521 0.017656
GO:0010972 negative regulation of G2/M transition of mitotic cell cycle 33.33% (1/3) 7.6 0.005134 0.017725
GO:1902750 negative regulation of cell cycle G2/M phase transition 33.33% (1/3) 7.6 0.005134 0.017725
GO:0071479 cellular response to ionizing radiation 33.33% (1/3) 7.56 0.005287 0.017751
GO:0044786 cell cycle DNA replication 33.33% (1/3) 7.52 0.005439 0.018099
GO:0044773 mitotic DNA damage checkpoint signaling 33.33% (1/3) 7.48 0.005592 0.01844
GO:0002039 p53 binding 33.33% (1/3) 7.44 0.005745 0.018775
GO:0043462 regulation of ATP-dependent activity 33.33% (1/3) 7.35 0.006128 0.019847
GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity 33.33% (1/3) 7.29 0.006357 0.020231
GO:1904029 regulation of cyclin-dependent protein kinase activity 33.33% (1/3) 7.29 0.006357 0.020231
GO:0044774 mitotic DNA integrity checkpoint signaling 33.33% (1/3) 7.26 0.00651 0.020539
GO:0016592 mediator complex 33.33% (1/3) 7.21 0.006739 0.021081
GO:2001021 negative regulation of response to DNA damage stimulus 33.33% (1/3) 7.19 0.006815 0.021139
GO:2000779 regulation of double-strand break repair 33.33% (1/3) 7.15 0.007045 0.021666
GO:0044815 DNA packaging complex 33.33% (1/3) 7.13 0.007121 0.021719
GO:0000217 DNA secondary structure binding 33.33% (1/3) 7.07 0.007426 0.022279
GO:0003684 damaged DNA binding 33.33% (1/3) 7.07 0.007426 0.022279
GO:0043279 response to alkaloid 33.33% (1/3) 7.0 0.007808 0.022327
GO:0000077 DNA damage checkpoint signaling 33.33% (1/3) 7.04 0.007579 0.022371
GO:0016363 nuclear matrix 33.33% (1/3) 7.03 0.007656 0.022415
GO:0065009 regulation of molecular function 66.67% (2/3) 3.68 0.007785 0.022436
GO:0007292 female gamete generation 33.33% (1/3) 7.01 0.007732 0.022459
GO:0005524 ATP binding 66.67% (2/3) 3.7 0.007575 0.022541
GO:0042770 signal transduction in response to DNA damage 33.33% (1/3) 6.89 0.008419 0.023886
GO:0006261 DNA-templated DNA replication 33.33% (1/3) 6.86 0.008572 0.023948
GO:0061982 meiosis I cell cycle process 33.33% (1/3) 6.86 0.008572 0.023948
GO:0071897 DNA biosynthetic process 33.33% (1/3) 6.81 0.008877 0.024066
GO:0019899 enzyme binding 66.67% (2/3) 3.6 0.008684 0.024079
GO:0009295 nucleoid 33.33% (1/3) 6.8 0.008953 0.024094
GO:0032559 adenyl ribonucleotide binding 66.67% (2/3) 3.6 0.00878 0.024161
GO:0030554 adenyl nucleotide binding 66.67% (2/3) 3.59 0.008868 0.024222
GO:0090329 regulation of DNA-templated DNA replication 33.33% (1/3) 6.76 0.009182 0.02453
GO:0031570 DNA integrity checkpoint signaling 33.33% (1/3) 6.75 0.009258 0.024555
GO:0035639 purine ribonucleoside triphosphate binding 66.67% (2/3) 3.5 0.009967 0.026057
GO:0065004 protein-DNA complex assembly 33.33% (1/3) 6.65 0.009945 0.026185
GO:0000723 telomere maintenance 33.33% (1/3) 6.57 0.010478 0.027007
GO:0032200 telomere organization 33.33% (1/3) 6.57 0.010478 0.027007
GO:0010389 regulation of G2/M transition of mitotic cell cycle 33.33% (1/3) 6.56 0.010554 0.027013
GO:0000228 nuclear chromosome 33.33% (1/3) 6.5 0.011012 0.027604
GO:0007093 mitotic cell cycle checkpoint signaling 33.33% (1/3) 6.5 0.011012 0.027604
GO:1902749 regulation of cell cycle G2/M phase transition 33.33% (1/3) 6.51 0.010935 0.027794
GO:0006275 regulation of DNA replication 33.33% (1/3) 6.45 0.011392 0.028365
GO:0032555 purine ribonucleotide binding 66.67% (2/3) 3.39 0.011562 0.0284
GO:0000018 regulation of DNA recombination 33.33% (1/3) 6.4 0.011773 0.028537
GO:0022607 cellular component assembly 66.67% (2/3) 3.39 0.011543 0.028546
GO:0017076 purine nucleotide binding 66.67% (2/3) 3.38 0.011708 0.028567
GO:0010212 response to ionizing radiation 33.33% (1/3) 6.35 0.01223 0.028879
GO:0032553 ribonucleotide binding 66.67% (2/3) 3.35 0.012199 0.028993
GO:0008340 determination of adult lifespan 33.33% (1/3) 6.33 0.012382 0.029051
GO:0006282 regulation of DNA repair 33.33% (1/3) 6.36 0.012154 0.029074
GO:0051053 negative regulation of DNA metabolic process 33.33% (1/3) 6.36 0.012154 0.029074
GO:0000075 cell cycle checkpoint signaling 33.33% (1/3) 6.19 0.013676 0.031283
GO:1901991 negative regulation of mitotic cell cycle phase transition 33.33% (1/3) 6.19 0.013676 0.031283
GO:0071900 regulation of protein serine/threonine kinase activity 33.33% (1/3) 6.21 0.013448 0.031349
GO:0097367 carbohydrate derivative binding 66.67% (2/3) 3.27 0.013611 0.03153
GO:0071215 cellular response to abscisic acid stimulus 33.33% (1/3) 6.12 0.014284 0.032472
GO:0006260 DNA replication 33.33% (1/3) 6.05 0.014968 0.033609
GO:0071824 protein-DNA complex subunit organization 33.33% (1/3) 6.05 0.014968 0.033609
GO:0045930 negative regulation of mitotic cell cycle 33.33% (1/3) 6.01 0.015424 0.034422
GO:1901988 negative regulation of cell cycle phase transition 33.33% (1/3) 5.89 0.016791 0.03702
GO:0051260 protein homooligomerization 33.33% (1/3) 5.89 0.016715 0.037076
GO:0070417 cellular response to cold 33.33% (1/3) 5.86 0.01717 0.037406
GO:0006996 organelle organization 66.67% (2/3) 3.1 0.017289 0.037442
GO:0042631 cellular response to water deprivation 33.33% (1/3) 5.86 0.017094 0.037464
GO:0071462 cellular response to water stimulus 33.33% (1/3) 5.81 0.017777 0.038272
GO:0097306 cellular response to alcohol 33.33% (1/3) 5.78 0.01808 0.038698
GO:0090304 nucleic acid metabolic process 66.67% (2/3) 3.01 0.019282 0.04103
GO:2001020 regulation of response to DNA damage stimulus 33.33% (1/3) 5.68 0.019444 0.041137
GO:0043168 anion binding 66.67% (2/3) 2.98 0.020246 0.042342
GO:0003677 DNA binding 66.67% (2/3) 2.98 0.020186 0.04246
GO:0071229 cellular response to acid chemical 33.33% (1/3) 5.6 0.020504 0.04264
GO:0043228 non-membrane-bounded organelle 66.67% (2/3) 2.92 0.022015 0.044517
GO:0043232 intracellular non-membrane-bounded organelle 66.67% (2/3) 2.92 0.022015 0.044517
GO:0045859 regulation of protein kinase activity 33.33% (1/3) 5.5 0.021942 0.044865
GO:0044260 cellular macromolecule metabolic process 66.67% (2/3) 2.93 0.021707 0.044886
GO:0010948 negative regulation of cell cycle process 33.33% (1/3) 5.5 0.021866 0.044961
GO:0051321 meiotic cell cycle 33.33% (1/3) 5.39 0.02368 0.047621
GO:0043549 regulation of kinase activity 33.33% (1/3) 5.37 0.023907 0.047814
Enriched Clades (corrected p-value < 0.05) (download table)
Clade % in cluster Enrichment log2 p-value Corrected p-value Gene Family Method
No enriched Clades found
Similar Clusters (download table)
Species Clustering Method Target Jaccard index Gene Family Method (for comparison) Actions
No similar clusters found
Sequences (3) (download table)

InterPro Domains

GO Terms

Family Terms