GO:0004222: metalloendopeptidase activity (Molecular function)

"Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions." [GOC:mah, https://www.ebi.ac.uk/merops/about/glossary.shtml#CATTYPE, https://www.ebi.ac.uk/merops/about/glossary.shtml#ENDOPEPTIDASE]


There are 915 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_783 Solanum tuberosum Agria 66.67 % 5e-06 2.8e-05
Cluster_130 Solanum tuberosum Agria 4.49 % 6e-06 0.000175
Cluster_210 Solanum tuberosum Agria 2.17 % 0.006731 0.048655
Cluster_216 Solanum tuberosum Agria 1.9 % 0.008684 0.039363
Cluster_152 Solanum tuberosum Agria 2.5 % 0.000559 0.005669
Sequences (915) (download table)

Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro Domains

Family Terms