"An intracellular protein kinase cascade containing at least ERK1 or ERK2 (MAPKs), a MEK (a MAPKK) and a MAP3K. The cascade may involve 4 different kinases, as it can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier to transmit a signal within a cell." [GOC:add, GOC:signaling, ISBN:0121245462, ISBN:0896039986, PMID:20811974, PMID:28903453]
There are 338 sequences with this label.
| Name | Species | % in cluster | p-value | corrected p-value | action |
|---|---|---|---|---|---|
| Cluster_110 | Solanum tuberosum Agria | 2.74 % | 0.000224 | 0.001751 |