GO:0070822: Sin3-type complex (Cellular component)

"Any of a number of evolutionarily conserved histone deacetylase complexes (HDACs) containing a core consisting of a paired amphipathic helix motif protein (e.g. Sin3p in S. cerevisiae, Pst1 in S. pombe or Sin3A in mammals) at least one class I histone deacetylase (e.g. Rpd3p in S. cerevisiae, Clr6 in S. pombe, or HDAC1 and HDAC2 in mammals), and at least one WD40 repeat protein (e.g. Ume1p in S. cerevisiae, Prw1 in S. pombe, or RbAp46 and RbAp48 in mammals). These complexes also contain a variable number of other proteins that direct histone binding, DNA binding, or add other functionality to the complex." [PMID:15565322, PMID:18292778]


There are 458 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_134 Solanum tuberosum Agria 2.67 % 0.001736 0.014481
Cluster_172 Solanum tuberosum Agria 4.62 % 2.1e-05 0.000383
Cluster_97 Solanum tuberosum Agria 1.56 % 0.004949 0.036025
Sequences (458) (download table)

Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro Domains

Family Terms