"An inflammasome complex that consists of three components, NLRP3 (NALP3), PYCARD and caspase-1. It is activated upon exposure to whole pathogens, as well as a number of structurally diverse pathogen- and danger-associated molecular patterns (PAMPs and DAMPs) and environmental irritants. Whole pathogens demonstrated to activate the NLRP3 inflammasome complex include the fungi Candida albicans and Saccharomyces cerevisiae, bacteria that produce pore-forming toxins, including Listeria monocytogenes and Staphylococcus aureus, and viruses such as Sendai virus, adenovirus, and influenza virus." [GOC:add, GOC:BHF, GOC:vp, PMID:20303873]
There are 76 sequences with this label.
| Name | Species | % in cluster | p-value | corrected p-value | action |
|---|---|---|---|---|---|
| Cluster_251 | Solanum tuberosum Agria | 1.69 % | 0.007525 | 0.048031 |