GO:0097193: intrinsic apoptotic signaling pathway (Biological process)

"The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway starts with reception of an intracellular signal (e.g. DNA damage, endoplasmic reticulum stress, oxidative stress etc.), and ends when the execution phase of apoptosis is triggered. The intrinsic apoptotic signaling pathway is crucially regulated by permeabilization of the mitochondrial outer membrane (MOMP)." [GOC:mtg_apoptosis, GOC:yaf, PMID:11919192, PMID:17340152, PMID:18852119]


There are 642 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_553 Solanum tuberosum Agria 20.0 % 0.010699 0.04241
Cluster_818 Solanum tuberosum Agria 33.33 % 0.006433 0.022676
Cluster_172 Solanum tuberosum Agria 4.62 % 0.00038 0.003065
Cluster_226 Solanum tuberosum Agria 3.28 % 0.000144 0.003112
Sequences (642) (download table)

Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro Domains

Family Terms