GO:0140766: siRNA-mediated gene silencing (Biological process)

"A post-transcriptional gene silencing pathway in which small interfering RNAs (siRNAs) elicit silencing of specific target genes. siRNAs are 21-23 nucleotide RNA duplexes that are fully complementary to their target mRNA. siRNAs can be exported and act in other cells, including in germline cells. Once incorporated into a RNA-induced silencing complex (RISC), siRNAs can downregulate gene expression by either of two posttranscriptional mechanisms: endonucleolytic cleavage of the mRNA or mRNA translational repression. siRNAs are present in lower animals and plants, but not found in mammals; whereas miRNAs are present in all the animals and in plants." [PMID:26372022]


There are 78 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_229 Solanum tuberosum Agria 2.35 % 7e-05 0.003144
Cluster_721 Solanum tuberosum Agria 50.0 % 0.000307 0.013302
Sequences (78) (download table)

InterPro Domains

GO Terms

Family Terms