SOLTUB.AGRIA.G00000022617


Description : Kinase family protein


Gene families : OG_02_0009576 (Orthogroups with 8 Potato genotypes) Phylogenetic Tree(s): No tree available for this family

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR Network (HRR 50 & PCC 0.5): SOLTUB.AGRIA.G00000022617
Cluster HCCA Clusters (HRR 50 & PCC 0.5): Cluster_88


Type GO Term Name Evidence Source
BP GO:0001666 response to hypoxia IEA AHRD
BP GO:0001845 phagolysosome assembly IEA AHRD
BP GO:0002229 defense response to oomycetes IEA AHRD
MF GO:0004709 MAP kinase kinase kinase activity IEA AHRD
MF GO:0004712 protein serine/threonine/tyrosine kinase activity IEA AHRD
MF GO:0004713 protein tyrosine kinase activity IEA AHRD
MF GO:0005524 ATP binding IEA AHRD
CC GO:0005634 nucleus IEA AHRD
CC GO:0005769 early endosome IEA AHRD
CC GO:0005789 endoplasmic reticulum membrane IEA AHRD
CC GO:0005802 trans-Golgi network IEA AHRD
CC GO:0005829 cytosol IEA AHRD
CC GO:0005886 plasma membrane IEA AHRD
CC GO:0005938 cell cortex IEA AHRD
BP GO:0006935 chemotaxis IEA AHRD
BP GO:0007254 JNK cascade IEA AHRD
BP GO:0009414 response to water deprivation IEA AHRD
BP GO:0009651 response to salt stress IEA AHRD
BP GO:0009658 chloroplast organization IEA AHRD
BP GO:0009686 gibberellin biosynthetic process IEA AHRD
BP GO:0009744 response to sucrose IEA AHRD
BP GO:0009750 response to fructose IEA AHRD
BP GO:0009788 negative regulation of abscisic acid-activated signaling pathway IEA AHRD
BP GO:0010105 negative regulation of ethylene-activated signaling pathway IEA AHRD
BP GO:0010182 sugar mediated signaling pathway IEA AHRD
CC GO:0012510 trans-Golgi network transport vesicle membrane IEA AHRD
BP GO:0016572 obsolete histone phosphorylation IEA AHRD
BP GO:0018107 peptidyl-threonine phosphorylation IEA AHRD
MF GO:0019901 protein kinase binding IEA AHRD
BP GO:0030036 actin cytoskeleton organization IEA AHRD
CC GO:0030426 growth cone IEA AHRD
CC GO:0030670 phagocytic vesicle membrane IEA AHRD
CC GO:0032010 phagolysosome IEA AHRD
BP GO:0036289 peptidyl-serine autophosphorylation IEA AHRD
MF GO:0042803 protein homodimerization activity IEA AHRD
BP GO:0043507 positive regulation of JUN kinase activity IEA AHRD
BP GO:0045893 positive regulation of DNA-templated transcription IEA AHRD
BP GO:0048510 regulation of timing of transition from vegetative to reproductive phase IEA AHRD
BP GO:0050829 defense response to Gram-negative bacterium IEA AHRD
BP GO:0070374 positive regulation of ERK1 and ERK2 cascade IEA AHRD
MF GO:0106310 protein serine kinase activity IEA AHRD
BP GO:1900150 regulation of defense response to fungus IEA AHRD
BP GO:1900424 regulation of defense response to bacterium IEA AHRD
BP GO:2000031 regulation of salicylic acid mediated signaling pathway IEA AHRD
BP GO:2000035 regulation of stem cell division IEA AHRD
BP GO:2000069 regulation of post-embryonic root development IEA AHRD
BP GO:2000672 negative regulation of motor neuron apoptotic process IEA AHRD
Type GO Term Name Evidence Source
MF GO:0000155 phosphorelay sensor kinase activity IEP Predict GO terms from Neighborhoods
BP GO:0000226 microtubule cytoskeleton organization IEP Predict GO terms from Neighborhoods
BP GO:0001578 microtubule bundle formation IEP Predict GO terms from Neighborhoods
MF GO:0002020 protease binding IEP Predict GO terms from Neighborhoods
MF GO:0004673 protein histidine kinase activity IEP Predict GO terms from Neighborhoods
MF GO:0005452 solute:inorganic anion antiporter activity IEP Predict GO terms from Neighborhoods
CC GO:0005765 lysosomal membrane IEP Predict GO terms from Neighborhoods
CC GO:0005774 vacuolar membrane IEP Predict GO terms from Neighborhoods
CC GO:0005813 centrosome IEP Predict GO terms from Neighborhoods
CC GO:0005815 microtubule organizing center IEP Predict GO terms from Neighborhoods
CC GO:0005874 microtubule IEP Predict GO terms from Neighborhoods
CC GO:0005881 cytoplasmic microtubule IEP Predict GO terms from Neighborhoods
CC GO:0005929 cilium IEP Predict GO terms from Neighborhoods
BP GO:0006066 alcohol metabolic process IEP Predict GO terms from Neighborhoods
BP GO:0006469 negative regulation of protein kinase activity IEP Predict GO terms from Neighborhoods
BP GO:0006810 transport IEP Predict GO terms from Neighborhoods
BP GO:0006811 ion transport IEP Predict GO terms from Neighborhoods
BP GO:0006817 phosphate ion transport IEP Predict GO terms from Neighborhoods
BP GO:0007017 microtubule-based process IEP Predict GO terms from Neighborhoods
BP GO:0007026 negative regulation of microtubule depolymerization IEP Predict GO terms from Neighborhoods
BP GO:0007154 cell communication IEP Predict GO terms from Neighborhoods
BP GO:0007588 excretion IEP Predict GO terms from Neighborhoods
BP GO:0007623 circadian rhythm IEP Predict GO terms from Neighborhoods
CC GO:0008352 katanin complex IEP Predict GO terms from Neighborhoods
MF GO:0008509 anion transmembrane transporter activity IEP Predict GO terms from Neighborhoods
MF GO:0008519 ammonium transmembrane transporter activity IEP Predict GO terms from Neighborhoods
BP GO:0009266 response to temperature stimulus IEP Predict GO terms from Neighborhoods
BP GO:0009409 response to cold IEP Predict GO terms from Neighborhoods
CC GO:0009524 phragmoplast IEP Predict GO terms from Neighborhoods
BP GO:0009561 megagametogenesis IEP Predict GO terms from Neighborhoods
CC GO:0009574 preprophase band IEP Predict GO terms from Neighborhoods
BP GO:0009584 detection of visible light IEP Predict GO terms from Neighborhoods
BP GO:0009606 tropism IEP Predict GO terms from Neighborhoods
BP GO:0009638 phototropism IEP Predict GO terms from Neighborhoods
BP GO:0009649 entrainment of circadian clock IEP Predict GO terms from Neighborhoods
BP GO:0009653 anatomical structure morphogenesis IEP Predict GO terms from Neighborhoods
BP GO:0009687 abscisic acid metabolic process IEP Predict GO terms from Neighborhoods
BP GO:0009719 response to endogenous stimulus IEP Predict GO terms from Neighborhoods
BP GO:0009725 response to hormone IEP Predict GO terms from Neighborhoods
BP GO:0009734 auxin-activated signaling pathway IEP Predict GO terms from Neighborhoods
BP GO:0009800 cinnamic acid biosynthetic process IEP Predict GO terms from Neighborhoods
MF GO:0009881 photoreceptor activity IEP Predict GO terms from Neighborhoods
MF GO:0009883 red or far-red light photoreceptor activity IEP Predict GO terms from Neighborhoods
CC GO:0009898 cytoplasmic side of plasma membrane IEP Predict GO terms from Neighborhoods
BP GO:0009902 chloroplast relocation IEP Predict GO terms from Neighborhoods
BP GO:0009903 chloroplast avoidance movement IEP Predict GO terms from Neighborhoods
BP GO:0009904 chloroplast accumulation movement IEP Predict GO terms from Neighborhoods
CC GO:0010008 endosome membrane IEP Predict GO terms from Neighborhoods
BP GO:0010015 root morphogenesis IEP Predict GO terms from Neighborhoods
BP GO:0010020 chloroplast fission IEP Predict GO terms from Neighborhoods
BP GO:0010029 regulation of seed germination IEP Predict GO terms from Neighborhoods
BP GO:0010036 response to boron-containing substance IEP Predict GO terms from Neighborhoods
BP GO:0010044 response to aluminum ion IEP Predict GO terms from Neighborhoods
BP GO:0010098 suspensor development IEP Predict GO terms from Neighborhoods
BP GO:0010101 post-embryonic root morphogenesis IEP Predict GO terms from Neighborhoods
BP GO:0010102 lateral root morphogenesis IEP Predict GO terms from Neighborhoods
BP GO:0010148 transpiration IEP Predict GO terms from Neighborhoods
BP GO:0010161 red light signaling pathway IEP Predict GO terms from Neighborhoods
BP GO:0010202 response to low fluence red light stimulus IEP Predict GO terms from Neighborhoods
BP GO:0010205 photoinhibition IEP Predict GO terms from Neighborhoods
BP GO:0010244 response to low fluence blue light stimulus by blue low-fluence system IEP Predict GO terms from Neighborhoods
BP GO:0010310 regulation of hydrogen peroxide metabolic process IEP Predict GO terms from Neighborhoods
BP GO:0010344 seed oilbody biogenesis IEP Predict GO terms from Neighborhoods
BP GO:0010360 negative regulation of anion channel activity IEP Predict GO terms from Neighborhoods
BP GO:0010374 stomatal complex development IEP Predict GO terms from Neighborhoods
BP GO:0010600 regulation of auxin biosynthetic process IEP Predict GO terms from Neighborhoods
BP GO:0010617 circadian regulation of calcium ion oscillation IEP Predict GO terms from Neighborhoods
BP GO:0010639 negative regulation of organelle organization IEP Predict GO terms from Neighborhoods
BP GO:0010726 positive regulation of hydrogen peroxide metabolic process IEP Predict GO terms from Neighborhoods
BP GO:0010728 regulation of hydrogen peroxide biosynthetic process IEP Predict GO terms from Neighborhoods
BP GO:0010729 positive regulation of hydrogen peroxide biosynthetic process IEP Predict GO terms from Neighborhoods
BP GO:0010976 positive regulation of neuron projection development IEP Predict GO terms from Neighborhoods
CC GO:0012505 endomembrane system IEP Predict GO terms from Neighborhoods
MF GO:0015075 ion transmembrane transporter activity IEP Predict GO terms from Neighborhoods
MF GO:0015103 inorganic anion transmembrane transporter activity IEP Predict GO terms from Neighborhoods
MF GO:0015114 phosphate ion transmembrane transporter activity IEP Predict GO terms from Neighborhoods
MF GO:0015119 hexose phosphate transmembrane transporter activity IEP Predict GO terms from Neighborhoods
MF GO:0015152 glucose-6-phosphate transmembrane transporter activity IEP Predict GO terms from Neighborhoods
MF GO:0015291 secondary active transmembrane transporter activity IEP Predict GO terms from Neighborhoods
MF GO:0015297 antiporter activity IEP Predict GO terms from Neighborhoods
MF GO:0015301 obsolete anion:anion antiporter activity IEP Predict GO terms from Neighborhoods
MF GO:0015315 organophosphate:inorganic phosphate antiporter activity IEP Predict GO terms from Neighborhoods
MF GO:0015318 inorganic molecular entity transmembrane transporter activity IEP Predict GO terms from Neighborhoods
MF GO:0015398 high-affinity secondary active ammonium transmembrane transporter activity IEP Predict GO terms from Neighborhoods
MF GO:0015526 hexose-phosphate:inorganic phosphate antiporter activity IEP Predict GO terms from Neighborhoods
MF GO:0015605 organophosphate ester transmembrane transporter activity IEP Predict GO terms from Neighborhoods
BP GO:0015698 inorganic anion transport IEP Predict GO terms from Neighborhoods
BP GO:0015712 hexose phosphate transport IEP Predict GO terms from Neighborhoods
BP GO:0015760 glucose-6-phosphate transport IEP Predict GO terms from Neighborhoods
BP GO:0015837 amine transport IEP Predict GO terms from Neighborhoods
BP GO:0015843 methylammonium transport IEP Predict GO terms from Neighborhoods
MF GO:0016207 4-coumarate-CoA ligase activity IEP Predict GO terms from Neighborhoods
MF GO:0016405 CoA-ligase activity IEP Predict GO terms from Neighborhoods
CC GO:0016514 SWI/SNF complex IEP Predict GO terms from Neighborhoods
MF GO:0016775 phosphotransferase activity, nitrogenous group as acceptor IEP Predict GO terms from Neighborhoods
MF GO:0016878 acid-thiol ligase activity IEP Predict GO terms from Neighborhoods
BP GO:0017006 protein-tetrapyrrole linkage IEP Predict GO terms from Neighborhoods
BP GO:0017007 protein-bilin linkage IEP Predict GO terms from Neighborhoods
BP GO:0017009 protein-phycocyanobilin linkage IEP Predict GO terms from Neighborhoods
BP GO:0017012 protein-phytochromobilin linkage IEP Predict GO terms from Neighborhoods
BP GO:0018298 obsolete protein-chromophore linkage IEP Predict GO terms from Neighborhoods
MF GO:0018858 benzoate-CoA ligase activity IEP Predict GO terms from Neighborhoods
BP GO:0018904 ether metabolic process IEP Predict GO terms from Neighborhoods
BP GO:0019750 chloroplast localization IEP Predict GO terms from Neighborhoods
BP GO:0019755 one-carbon compound transport IEP Predict GO terms from Neighborhoods
MF GO:0022804 active transmembrane transporter activity IEP Predict GO terms from Neighborhoods
MF GO:0022853 active ion transmembrane transporter activity IEP Predict GO terms from Neighborhoods
BP GO:0023052 signaling IEP Predict GO terms from Neighborhoods
BP GO:0030901 midbrain development IEP Predict GO terms from Neighborhoods
BP GO:0031110 regulation of microtubule polymerization or depolymerization IEP Predict GO terms from Neighborhoods
BP GO:0031111 negative regulation of microtubule polymerization or depolymerization IEP Predict GO terms from Neighborhoods
BP GO:0031112 positive regulation of microtubule polymerization or depolymerization IEP Predict GO terms from Neighborhoods
BP GO:0031114 regulation of microtubule depolymerization IEP Predict GO terms from Neighborhoods
BP GO:0031117 positive regulation of microtubule depolymerization IEP Predict GO terms from Neighborhoods
BP GO:0031324 negative regulation of cellular metabolic process IEP Predict GO terms from Neighborhoods
MF GO:0031516 far-red light photoreceptor activity IEP Predict GO terms from Neighborhoods
MF GO:0031517 red light photoreceptor activity IEP Predict GO terms from Neighborhoods
BP GO:0031648 protein destabilization IEP Predict GO terms from Neighborhoods
CC GO:0031902 late endosome membrane IEP Predict GO terms from Neighborhoods
BP GO:0032410 negative regulation of transporter activity IEP Predict GO terms from Neighborhoods
BP GO:0032413 negative regulation of ion transmembrane transporter activity IEP Predict GO terms from Neighborhoods
BP GO:0032501 multicellular organismal process IEP Predict GO terms from Neighborhoods
BP GO:0032502 developmental process IEP Predict GO terms from Neighborhoods
BP GO:0032886 regulation of microtubule-based process IEP Predict GO terms from Neighborhoods
BP GO:0033043 regulation of organelle organization IEP Predict GO terms from Neighborhoods
CC GO:0033106 cis-Golgi network membrane IEP Predict GO terms from Neighborhoods
BP GO:0033494 ferulate metabolic process IEP Predict GO terms from Neighborhoods
BP GO:0033673 negative regulation of kinase activity IEP Predict GO terms from Neighborhoods
BP GO:0034220 ion transmembrane transport IEP Predict GO terms from Neighborhoods
BP GO:0035082 axoneme assembly IEP Predict GO terms from Neighborhoods
BP GO:0035435 phosphate ion transmembrane transport IEP Predict GO terms from Neighborhoods
BP GO:0035445 borate transmembrane transport IEP Predict GO terms from Neighborhoods
CC GO:0036020 endolysosome membrane IEP Predict GO terms from Neighborhoods
CC GO:0036513 Derlin-1 retrotranslocation complex IEP Predict GO terms from Neighborhoods
BP GO:0042548 regulation of photosynthesis, light reaction IEP Predict GO terms from Neighborhoods
BP GO:0042752 regulation of circadian rhythm IEP Predict GO terms from Neighborhoods
BP GO:0042753 positive regulation of circadian rhythm IEP Predict GO terms from Neighborhoods
BP GO:0042754 negative regulation of circadian rhythm IEP Predict GO terms from Neighborhoods
BP GO:0043155 negative regulation of photosynthesis, light reaction IEP Predict GO terms from Neighborhoods
BP GO:0043242 negative regulation of protein-containing complex disassembly IEP Predict GO terms from Neighborhoods
BP GO:0043243 positive regulation of protein-containing complex disassembly IEP Predict GO terms from Neighborhoods
BP GO:0043288 apocarotenoid metabolic process IEP Predict GO terms from Neighborhoods
BP GO:0043572 plastid fission IEP Predict GO terms from Neighborhoods
BP GO:0043966 histone H3 acetylation IEP Predict GO terms from Neighborhoods
BP GO:0044087 regulation of cellular component biogenesis IEP Predict GO terms from Neighborhoods
MF GO:0044877 protein-containing complex binding IEP Predict GO terms from Neighborhoods
BP GO:0046713 borate transport IEP Predict GO terms from Neighborhoods
MF GO:0046715 active borate transmembrane transporter activity IEP Predict GO terms from Neighborhoods
BP GO:0048511 rhythmic process IEP Predict GO terms from Neighborhoods
BP GO:0048574 long-day photoperiodism, flowering IEP Predict GO terms from Neighborhoods
BP GO:0048646 anatomical structure formation involved in morphogenesis IEP Predict GO terms from Neighborhoods
MF GO:0050563 trans-feruloyl-CoA synthase activity IEP Predict GO terms from Neighborhoods
BP GO:0050801 ion homeostasis IEP Predict GO terms from Neighborhoods
BP GO:0051013 microtubule severing IEP Predict GO terms from Neighborhoods
BP GO:0051128 regulation of cellular component organization IEP Predict GO terms from Neighborhoods
BP GO:0051129 negative regulation of cellular component organization IEP Predict GO terms from Neighborhoods
BP GO:0051172 negative regulation of nitrogen compound metabolic process IEP Predict GO terms from Neighborhoods
BP GO:0051234 establishment of localization IEP Predict GO terms from Neighborhoods
BP GO:0051258 protein polymerization IEP Predict GO terms from Neighborhoods
BP GO:0051270 obsolete regulation of cellular component movement IEP Predict GO terms from Neighborhoods
BP GO:0051480 regulation of cytosolic calcium ion concentration IEP Predict GO terms from Neighborhoods
BP GO:0051493 regulation of cytoskeleton organization IEP Predict GO terms from Neighborhoods
BP GO:0051495 positive regulation of cytoskeleton organization IEP Predict GO terms from Neighborhoods
BP GO:0051640 organelle localization IEP Predict GO terms from Neighborhoods
BP GO:0051644 plastid localization IEP Predict GO terms from Neighborhoods
BP GO:0051656 establishment of organelle localization IEP Predict GO terms from Neighborhoods
BP GO:0051667 establishment of plastid localization IEP Predict GO terms from Neighborhoods
BP GO:0051726 regulation of cell cycle IEP Predict GO terms from Neighborhoods
BP GO:0051972 regulation of telomerase activity IEP Predict GO terms from Neighborhoods
BP GO:0051973 positive regulation of telomerase activity IEP Predict GO terms from Neighborhoods
CC GO:0055028 cortical microtubule IEP Predict GO terms from Neighborhoods
BP GO:0055046 microgametogenesis IEP Predict GO terms from Neighborhoods
BP GO:0055062 phosphate ion homeostasis IEP Predict GO terms from Neighborhoods
MF GO:0060590 ATPase regulator activity IEP Predict GO terms from Neighborhoods
BP GO:0060628 regulation of ER to Golgi vesicle-mediated transport IEP Predict GO terms from Neighborhoods
MF GO:0061513 glucose 6-phosphate:inorganic phosphate antiporter activity IEP Predict GO terms from Neighborhoods
BP GO:0065008 regulation of biological quality IEP Predict GO terms from Neighborhoods
BP GO:0070613 regulation of protein processing IEP Predict GO terms from Neighborhoods
MF GO:0070840 dynein complex binding IEP Predict GO terms from Neighborhoods
BP GO:0071491 cellular response to red light IEP Predict GO terms from Neighborhoods
BP GO:0071702 organic substance transport IEP Predict GO terms from Neighborhoods
BP GO:0072488 ammonium transmembrane transport IEP Predict GO terms from Neighborhoods
BP GO:0072506 trivalent inorganic anion homeostasis IEP Predict GO terms from Neighborhoods
BP GO:0080029 cellular response to boron-containing substance levels IEP Predict GO terms from Neighborhoods
MF GO:0080139 borate efflux transmembrane transporter activity IEP Predict GO terms from Neighborhoods
BP GO:0080159 zygote elongation IEP Predict GO terms from Neighborhoods
BP GO:0080181 lateral root branching IEP Predict GO terms from Neighborhoods
BP GO:0090382 phagosome maturation IEP Predict GO terms from Neighborhoods
BP GO:0090697 post-embryonic plant organ morphogenesis IEP Predict GO terms from Neighborhoods
BP GO:0090698 post-embryonic plant morphogenesis IEP Predict GO terms from Neighborhoods
BP GO:0098656 anion transmembrane transport IEP Predict GO terms from Neighborhoods
BP GO:0098660 inorganic ion transmembrane transport IEP Predict GO terms from Neighborhoods
BP GO:0098661 inorganic anion transmembrane transport IEP Predict GO terms from Neighborhoods
CC GO:0098852 lytic vacuole membrane IEP Predict GO terms from Neighborhoods
CC GO:0099080 supramolecular complex IEP Predict GO terms from Neighborhoods
CC GO:0099081 supramolecular polymer IEP Predict GO terms from Neighborhoods
CC GO:0099512 supramolecular fiber IEP Predict GO terms from Neighborhoods
CC GO:0099513 polymeric cytoskeletal fiber IEP Predict GO terms from Neighborhoods
MF GO:0106286 (E)-caffeate-CoA ligase activity IEP Predict GO terms from Neighborhoods
MF GO:0106290 trans-cinnamate-CoA ligase activity IEP Predict GO terms from Neighborhoods
BP GO:0120254 olefinic compound metabolic process IEP Predict GO terms from Neighborhoods
MF GO:0140299 small molecule sensor activity IEP Predict GO terms from Neighborhoods
MF GO:0140323 solute:anion antiporter activity IEP Predict GO terms from Neighborhoods
BP GO:1900140 regulation of seedling development IEP Predict GO terms from Neighborhoods
BP GO:1901615 organic hydroxy compound metabolic process IEP Predict GO terms from Neighborhoods
BP GO:1901879 regulation of protein depolymerization IEP Predict GO terms from Neighborhoods
BP GO:1901880 negative regulation of protein depolymerization IEP Predict GO terms from Neighborhoods
BP GO:1901881 positive regulation of protein depolymerization IEP Predict GO terms from Neighborhoods
BP GO:1902115 regulation of organelle assembly IEP Predict GO terms from Neighborhoods
BP GO:1902116 negative regulation of organelle assembly IEP Predict GO terms from Neighborhoods
BP GO:1902644 tertiary alcohol metabolic process IEP Predict GO terms from Neighborhoods
BP GO:1902905 positive regulation of supramolecular fiber organization IEP Predict GO terms from Neighborhoods
BP GO:1903317 regulation of protein maturation IEP Predict GO terms from Neighborhoods
BP GO:1903426 regulation of reactive oxygen species biosynthetic process IEP Predict GO terms from Neighborhoods
BP GO:1903428 positive regulation of reactive oxygen species biosynthetic process IEP Predict GO terms from Neighborhoods
BP GO:1903792 negative regulation of anion transport IEP Predict GO terms from Neighborhoods
BP GO:1903960 negative regulation of anion transmembrane transport IEP Predict GO terms from Neighborhoods
BP GO:1905156 negative regulation of photosynthesis IEP Predict GO terms from Neighborhoods
BP GO:2000379 positive regulation of reactive oxygen species metabolic process IEP Predict GO terms from Neighborhoods
BP GO:2000573 positive regulation of DNA biosynthetic process IEP Predict GO terms from Neighborhoods
InterPro domains Description Start Stop
IPR001245 Ser-Thr/Tyr_kinase_cat_dom 740 990
IPR011009 Kinase-like_dom_sf 726 989
No external refs found!