GO:0030433: ubiquitin-dependent ERAD pathway (Biological process)

"The series of steps necessary to target endoplasmic reticulum (ER)-resident proteins for degradation by the cytoplasmic proteasome. Begins with recognition of the ER-resident protein, includes retrotranslocation (dislocation) of the protein from the ER to the cytosol, protein ubiquitination necessary for correct substrate transfer, transport of the protein to the proteasome, and ends with degradation of the protein by the cytoplasmic proteasome." [GOC:mah, GOC:rb, PMID:14607247, PMID:19520858]


There are 900 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_124 Solanum tuberosum Agria 2.06 % 0.003472 0.031935
Cluster_249 Solanum tuberosum Agria 4.4 % 0.000208 0.004523
Cluster_112 Solanum tuberosum Agria 5.71 % 7.5e-05 0.000751
Cluster_22 Solanum tuberosum Agria 5.74 % 0.0 0.000154
Cluster_262 Solanum tuberosum Agria 3.33 % 0.002994 0.030513
Cluster_203 Solanum tuberosum Agria 4.84 % 0.001028 0.025937
Cluster_119 Solanum tuberosum Agria 5.88 % 8e-06 0.000102
Cluster_81 Solanum tuberosum Agria 7.69 % 0.0 0.0
Sequences (900) (download table)

Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro Domains

Family Terms