SOLTUB.AGRIA.G00000021784


Description : eukaryotic translation initiation factor 2 (eIF-2) family protein


Gene families : OG_02_0009449 (Orthogroups with 8 Potato genotypes) Phylogenetic Tree(s): No tree available for this family

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR Network (HRR 50 & PCC 0.5): SOLTUB.AGRIA.G00000021784
Cluster HCCA Clusters (HRR 50 & PCC 0.5): Cluster_124


Type GO Term Name Evidence Source
BP GO:0001732 formation of cytoplasmic translation initiation complex IEA AHRD
MF GO:0003743 translation initiation factor activity IEA AHRD
MF GO:0003924 GTPase activity IEA AHRD
MF GO:0005515 protein binding IEA AHRD
MF GO:0005525 GTP binding IEA AHRD
CC GO:0005829 cytosol IEA AHRD
BP GO:0006446 regulation of translational initiation IEA AHRD
CC GO:0033290 eukaryotic 48S preinitiation complex IEA AHRD
BP GO:0042256 mature ribosome assembly IEA AHRD
Type GO Term Name Evidence Source
BP GO:0000028 ribosomal small subunit assembly IEP Predict GO terms from Neighborhoods
CC GO:0000118 histone deacetylase complex IEP Predict GO terms from Neighborhoods
BP GO:0000122 negative regulation of transcription by RNA polymerase II IEP Predict GO terms from Neighborhoods
CC GO:0000243 commitment complex IEP Predict GO terms from Neighborhoods
BP GO:0000245 spliceosomal complex assembly IEP Predict GO terms from Neighborhoods
BP GO:0000375 RNA splicing, via transesterification reactions IEP Predict GO terms from Neighborhoods
BP GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile IEP Predict GO terms from Neighborhoods
BP GO:0000381 regulation of alternative mRNA splicing, via spliceosome IEP Predict GO terms from Neighborhoods
BP GO:0000398 mRNA splicing, via spliceosome IEP Predict GO terms from Neighborhoods
MF GO:0001671 ATPase activator activity IEP Predict GO terms from Neighborhoods
BP GO:0001825 blastocyst formation IEP Predict GO terms from Neighborhoods
BP GO:0001835 blastocyst hatching IEP Predict GO terms from Neighborhoods
BP GO:0002021 response to dietary excess IEP Predict GO terms from Neighborhoods
BP GO:0002684 positive regulation of immune system process IEP Predict GO terms from Neighborhoods
BP GO:0002694 regulation of leukocyte activation IEP Predict GO terms from Neighborhoods
BP GO:0002696 positive regulation of leukocyte activation IEP Predict GO terms from Neighborhoods
MF GO:0003723 RNA binding IEP Predict GO terms from Neighborhoods
CC GO:0005657 replication fork IEP Predict GO terms from Neighborhoods
CC GO:0005681 spliceosomal complex IEP Predict GO terms from Neighborhoods
CC GO:0005684 U2-type spliceosomal complex IEP Predict GO terms from Neighborhoods
CC GO:0005685 U1 snRNP IEP Predict GO terms from Neighborhoods
CC GO:0005689 U12-type spliceosomal complex IEP Predict GO terms from Neighborhoods
CC GO:0005700 polytene chromosome IEP Predict GO terms from Neighborhoods
CC GO:0005788 endoplasmic reticulum lumen IEP Predict GO terms from Neighborhoods
BP GO:0006139 nucleobase-containing compound metabolic process IEP Predict GO terms from Neighborhoods
BP GO:0006270 DNA replication initiation IEP Predict GO terms from Neighborhoods
BP GO:0006271 DNA strand elongation involved in DNA replication IEP Predict GO terms from Neighborhoods
BP GO:0006396 RNA processing IEP Predict GO terms from Neighborhoods
BP GO:0006397 mRNA processing IEP Predict GO terms from Neighborhoods
BP GO:0006458 'de novo' protein folding IEP Predict GO terms from Neighborhoods
BP GO:0006725 cellular aromatic compound metabolic process IEP Predict GO terms from Neighborhoods
BP GO:0006839 mitochondrial transport IEP Predict GO terms from Neighborhoods
BP GO:0006928 obsolete movement of cell or subcellular component IEP Predict GO terms from Neighborhoods
BP GO:0007010 cytoskeleton organization IEP Predict GO terms from Neighborhoods
BP GO:0007369 gastrulation IEP Predict GO terms from Neighborhoods
BP GO:0007423 sensory organ development IEP Predict GO terms from Neighborhoods
BP GO:0007548 sex differentiation IEP Predict GO terms from Neighborhoods
BP GO:0007605 sensory perception of sound IEP Predict GO terms from Neighborhoods
MF GO:0008013 beta-catenin binding IEP Predict GO terms from Neighborhoods
MF GO:0008134 transcription factor binding IEP Predict GO terms from Neighborhoods
BP GO:0008360 regulation of cell shape IEP Predict GO terms from Neighborhoods
BP GO:0008380 RNA splicing IEP Predict GO terms from Neighborhoods
BP GO:0008587 imaginal disc-derived wing margin morphogenesis IEP Predict GO terms from Neighborhoods
BP GO:0008593 regulation of Notch signaling pathway IEP Predict GO terms from Neighborhoods
CC GO:0008622 epsilon DNA polymerase complex IEP Predict GO terms from Neighborhoods
CC GO:0008623 CHRAC IEP Predict GO terms from Neighborhoods
BP GO:0009886 post-embryonic animal morphogenesis IEP Predict GO terms from Neighborhoods
BP GO:0010721 negative regulation of cell development IEP Predict GO terms from Neighborhoods
BP GO:0016070 RNA metabolic process IEP Predict GO terms from Neighborhoods
BP GO:0016071 mRNA metabolic process IEP Predict GO terms from Neighborhoods
CC GO:0016363 nuclear matrix IEP Predict GO terms from Neighborhoods
CC GO:0016592 mediator complex IEP Predict GO terms from Neighborhoods
CC GO:0016604 nuclear body IEP Predict GO terms from Neighborhoods
CC GO:0016607 nuclear speck IEP Predict GO terms from Neighborhoods
CC GO:0017053 transcription repressor complex IEP Predict GO terms from Neighborhoods
BP GO:0017145 stem cell division IEP Predict GO terms from Neighborhoods
BP GO:0019219 regulation of nucleobase-containing compound metabolic process IEP Predict GO terms from Neighborhoods
MF GO:0019904 protein domain specific binding IEP Predict GO terms from Neighborhoods
BP GO:0022416 chaeta development IEP Predict GO terms from Neighborhoods
BP GO:0022612 gland morphogenesis IEP Predict GO terms from Neighborhoods
BP GO:0022616 DNA strand elongation IEP Predict GO terms from Neighborhoods
CC GO:0030018 Z disc IEP Predict GO terms from Neighborhoods
BP GO:0030097 hemopoiesis IEP Predict GO terms from Neighborhoods
BP GO:0030150 protein import into mitochondrial matrix IEP Predict GO terms from Neighborhoods
CC GO:0030176 integral component of endoplasmic reticulum membrane IEP Predict GO terms from Neighborhoods
BP GO:0030177 positive regulation of Wnt signaling pathway IEP Predict GO terms from Neighborhoods
MF GO:0030337 DNA polymerase processivity factor activity IEP Predict GO terms from Neighborhoods
BP GO:0030433 ubiquitin-dependent ERAD pathway IEP Predict GO terms from Neighborhoods
CC GO:0030532 small nuclear ribonucleoprotein complex IEP Predict GO terms from Neighborhoods
MF GO:0030544 Hsp70 protein binding IEP Predict GO terms from Neighborhoods
MF GO:0030628 pre-mRNA 3'-splice site binding IEP Predict GO terms from Neighborhoods
CC GO:0031010 ISWI-type complex IEP Predict GO terms from Neighborhoods
BP GO:0031017 exocrine pancreas development IEP Predict GO terms from Neighborhoods
BP GO:0031063 regulation of histone deacetylation IEP Predict GO terms from Neighborhoods
BP GO:0031065 positive regulation of histone deacetylation IEP Predict GO terms from Neighborhoods
MF GO:0031072 heat shock protein binding IEP Predict GO terms from Neighborhoods
BP GO:0031647 regulation of protein stability IEP Predict GO terms from Neighborhoods
BP GO:0032465 regulation of cytokinesis IEP Predict GO terms from Neighborhoods
CC GO:0032545 CURI complex IEP Predict GO terms from Neighborhoods
BP GO:0032781 positive regulation of ATP-dependent activity IEP Predict GO terms from Neighborhoods
BP GO:0032872 regulation of stress-activated MAPK cascade IEP Predict GO terms from Neighborhoods
BP GO:0032873 negative regulation of stress-activated MAPK cascade IEP Predict GO terms from Neighborhoods
CC GO:0034456 UTP-C complex IEP Predict GO terms from Neighborhoods
BP GO:0034641 cellular nitrogen compound metabolic process IEP Predict GO terms from Neighborhoods
CC GO:0034663 endoplasmic reticulum chaperone complex IEP Predict GO terms from Neighborhoods
BP GO:0035188 hatching IEP Predict GO terms from Neighborhoods
BP GO:0035264 multicellular organism growth IEP Predict GO terms from Neighborhoods
BP GO:0035967 cellular response to topologically incorrect protein IEP Predict GO terms from Neighborhoods
MF GO:0036002 pre-mRNA binding IEP Predict GO terms from Neighborhoods
BP GO:0042058 regulation of epidermal growth factor receptor signaling pathway IEP Predict GO terms from Neighborhoods
BP GO:0042078 germ-line stem cell division IEP Predict GO terms from Neighborhoods
BP GO:0042254 ribosome biogenesis IEP Predict GO terms from Neighborhoods
MF GO:0042393 histone binding IEP Predict GO terms from Neighborhoods
BP GO:0042461 photoreceptor cell development IEP Predict GO terms from Neighborhoods
CC GO:0042575 DNA polymerase complex IEP Predict GO terms from Neighborhoods
BP GO:0042689 regulation of crystal cell differentiation IEP Predict GO terms from Neighborhoods
BP GO:0042691 positive regulation of crystal cell differentiation IEP Predict GO terms from Neighborhoods
BP GO:0042766 obsolete nucleosome mobilization IEP Predict GO terms from Neighborhoods
CC GO:0043073 germ cell nucleus IEP Predict GO terms from Neighborhoods
BP GO:0043170 macromolecule metabolic process IEP Predict GO terms from Neighborhoods
BP GO:0043409 negative regulation of MAPK cascade IEP Predict GO terms from Neighborhoods
BP GO:0043462 regulation of ATP-dependent activity IEP Predict GO terms from Neighborhoods
BP GO:0043484 regulation of RNA splicing IEP Predict GO terms from Neighborhoods
BP GO:0043523 regulation of neuron apoptotic process IEP Predict GO terms from Neighborhoods
BP GO:0043524 negative regulation of neuron apoptotic process IEP Predict GO terms from Neighborhoods
CC GO:0043596 nuclear replication fork IEP Predict GO terms from Neighborhoods
BP GO:0043627 response to estrogen IEP Predict GO terms from Neighborhoods
BP GO:0044743 protein transmembrane import into intracellular organelle IEP Predict GO terms from Neighborhoods
BP GO:0044782 cilium organization IEP Predict GO terms from Neighborhoods
BP GO:0045292 mRNA cis splicing, via spliceosome IEP Predict GO terms from Neighborhoods
BP GO:0045444 fat cell differentiation IEP Predict GO terms from Neighborhoods
BP GO:0045570 regulation of imaginal disc growth IEP Predict GO terms from Neighborhoods
BP GO:0045572 positive regulation of imaginal disc growth IEP Predict GO terms from Neighborhoods
BP GO:0045597 positive regulation of cell differentiation IEP Predict GO terms from Neighborhoods
BP GO:0045610 regulation of hemocyte differentiation IEP Predict GO terms from Neighborhoods
BP GO:0045612 positive regulation of hemocyte differentiation IEP Predict GO terms from Neighborhoods
BP GO:0045619 regulation of lymphocyte differentiation IEP Predict GO terms from Neighborhoods
BP GO:0045621 positive regulation of lymphocyte differentiation IEP Predict GO terms from Neighborhoods
BP GO:0045637 regulation of myeloid cell differentiation IEP Predict GO terms from Neighborhoods
BP GO:0045639 positive regulation of myeloid cell differentiation IEP Predict GO terms from Neighborhoods
BP GO:0045646 regulation of erythrocyte differentiation IEP Predict GO terms from Neighborhoods
BP GO:0045648 positive regulation of erythrocyte differentiation IEP Predict GO terms from Neighborhoods
BP GO:0045747 positive regulation of Notch signaling pathway IEP Predict GO terms from Neighborhoods
BP GO:0046328 regulation of JNK cascade IEP Predict GO terms from Neighborhoods
BP GO:0046329 negative regulation of JNK cascade IEP Predict GO terms from Neighborhoods
BP GO:0046483 heterocycle metabolic process IEP Predict GO terms from Neighborhoods
MF GO:0047485 protein N-terminus binding IEP Predict GO terms from Neighborhoods
BP GO:0048024 regulation of mRNA splicing, via spliceosome IEP Predict GO terms from Neighborhoods
BP GO:0048546 digestive tract morphogenesis IEP Predict GO terms from Neighborhoods
BP GO:0048666 neuron development IEP Predict GO terms from Neighborhoods
BP GO:0050684 regulation of mRNA processing IEP Predict GO terms from Neighborhoods
MF GO:0050733 RS domain binding IEP Predict GO terms from Neighborhoods
BP GO:0050768 negative regulation of neurogenesis IEP Predict GO terms from Neighborhoods
BP GO:0050821 protein stabilization IEP Predict GO terms from Neighborhoods
BP GO:0050867 positive regulation of cell activation IEP Predict GO terms from Neighborhoods
BP GO:0050872 white fat cell differentiation IEP Predict GO terms from Neighborhoods
BP GO:0050954 sensory perception of mechanical stimulus IEP Predict GO terms from Neighborhoods
BP GO:0051084 'de novo' post-translational protein folding IEP Predict GO terms from Neighborhoods
BP GO:0051085 chaperone cofactor-dependent protein refolding IEP Predict GO terms from Neighborhoods
BP GO:0051094 positive regulation of developmental process IEP Predict GO terms from Neighborhoods
BP GO:0051249 regulation of lymphocyte activation IEP Predict GO terms from Neighborhoods
BP GO:0051251 positive regulation of lymphocyte activation IEP Predict GO terms from Neighborhoods
BP GO:0051252 regulation of RNA metabolic process IEP Predict GO terms from Neighborhoods
MF GO:0051787 misfolded protein binding IEP Predict GO terms from Neighborhoods
BP GO:0051788 response to misfolded protein IEP Predict GO terms from Neighborhoods
BP GO:0051961 negative regulation of nervous system development IEP Predict GO terms from Neighborhoods
BP GO:0060216 definitive hemopoiesis IEP Predict GO terms from Neighborhoods
BP GO:0060249 anatomical structure homeostasis IEP Predict GO terms from Neighborhoods
BP GO:0060271 cilium assembly IEP Predict GO terms from Neighborhoods
BP GO:0060612 adipose tissue development IEP Predict GO terms from Neighborhoods
BP GO:0060613 fat pad development IEP Predict GO terms from Neighborhoods
BP GO:0061448 connective tissue development IEP Predict GO terms from Neighborhoods
BP GO:0065002 intracellular protein transmembrane transport IEP Predict GO terms from Neighborhoods
BP GO:0070050 neuron cellular homeostasis IEP Predict GO terms from Neighborhoods
BP GO:0070302 regulation of stress-activated protein kinase signaling cascade IEP Predict GO terms from Neighborhoods
BP GO:0070303 negative regulation of stress-activated protein kinase signaling cascade IEP Predict GO terms from Neighborhoods
BP GO:0070585 protein localization to mitochondrion IEP Predict GO terms from Neighborhoods
CC GO:0070603 SWI/SNF superfamily-type complex IEP Predict GO terms from Neighborhoods
MF GO:0070990 snRNP binding IEP Predict GO terms from Neighborhoods
CC GO:0071004 U2-type prespliceosome IEP Predict GO terms from Neighborhoods
CC GO:0071005 U2-type precatalytic spliceosome IEP Predict GO terms from Neighborhoods
CC GO:0071006 U2-type catalytic step 1 spliceosome IEP Predict GO terms from Neighborhoods
CC GO:0071007 U2-type catalytic step 2 spliceosome IEP Predict GO terms from Neighborhoods
CC GO:0071010 prespliceosome IEP Predict GO terms from Neighborhoods
CC GO:0071011 precatalytic spliceosome IEP Predict GO terms from Neighborhoods
CC GO:0071012 catalytic step 1 spliceosome IEP Predict GO terms from Neighborhoods
CC GO:0071013 catalytic step 2 spliceosome IEP Predict GO terms from Neighborhoods
BP GO:0071163 DNA replication preinitiation complex assembly IEP Predict GO terms from Neighborhoods
BP GO:0071218 cellular response to misfolded protein IEP Predict GO terms from Neighborhoods
BP GO:0071684 organism emergence from protective structure IEP Predict GO terms from Neighborhoods
BP GO:0072576 liver morphogenesis IEP Predict GO terms from Neighborhoods
BP GO:0072655 establishment of protein localization to mitochondrion IEP Predict GO terms from Neighborhoods
CC GO:0072686 mitotic spindle IEP Predict GO terms from Neighborhoods
BP GO:0080135 regulation of cellular response to stress IEP Predict GO terms from Neighborhoods
CC GO:0089701 U2AF complex IEP Predict GO terms from Neighborhoods
BP GO:0090207 regulation of triglyceride metabolic process IEP Predict GO terms from Neighborhoods
BP GO:0090263 positive regulation of canonical Wnt signaling pathway IEP Predict GO terms from Neighborhoods
BP GO:0090304 nucleic acid metabolic process IEP Predict GO terms from Neighborhoods
BP GO:0090311 regulation of protein deacetylation IEP Predict GO terms from Neighborhoods
BP GO:0090312 positive regulation of protein deacetylation IEP Predict GO terms from Neighborhoods
CC GO:0097525 spliceosomal snRNP complex IEP Predict GO terms from Neighborhoods
CC GO:0101031 chaperone complex IEP Predict GO terms from Neighborhoods
CC GO:0120114 Sm-like protein family complex IEP Predict GO terms from Neighborhoods
CC GO:0140513 nuclear protein-containing complex IEP Predict GO terms from Neighborhoods
BP GO:0140529 CMG complex assembly IEP Predict GO terms from Neighborhoods
CC GO:0140535 intracellular protein-containing complex IEP Predict GO terms from Neighborhoods
MF GO:0140677 molecular function activator activity IEP Predict GO terms from Neighborhoods
BP GO:1901184 regulation of ERBB signaling pathway IEP Predict GO terms from Neighborhoods
BP GO:1901215 negative regulation of neuron death IEP Predict GO terms from Neighborhoods
BP GO:1901360 organic cyclic compound metabolic process IEP Predict GO terms from Neighborhoods
BP GO:1901532 regulation of hematopoietic progenitor cell differentiation IEP Predict GO terms from Neighborhoods
BP GO:1901534 positive regulation of hematopoietic progenitor cell differentiation IEP Predict GO terms from Neighborhoods
BP GO:1902036 regulation of hematopoietic stem cell differentiation IEP Predict GO terms from Neighborhoods
BP GO:1902038 positive regulation of hematopoietic stem cell differentiation IEP Predict GO terms from Neighborhoods
BP GO:1902105 regulation of leukocyte differentiation IEP Predict GO terms from Neighborhoods
BP GO:1902107 positive regulation of leukocyte differentiation IEP Predict GO terms from Neighborhoods
BP GO:1902292 cell cycle DNA replication initiation IEP Predict GO terms from Neighborhoods
BP GO:1902296 DNA strand elongation involved in cell cycle DNA replication IEP Predict GO terms from Neighborhoods
BP GO:1902315 nuclear cell cycle DNA replication initiation IEP Predict GO terms from Neighborhoods
BP GO:1902319 DNA strand elongation involved in nuclear cell cycle DNA replication IEP Predict GO terms from Neighborhoods
CC GO:1902494 catalytic complex IEP Predict GO terms from Neighborhoods
BP GO:1902975 mitotic DNA replication initiation IEP Predict GO terms from Neighborhoods
BP GO:1902983 DNA strand elongation involved in mitotic DNA replication IEP Predict GO terms from Neighborhoods
BP GO:1903311 regulation of mRNA metabolic process IEP Predict GO terms from Neighborhoods
BP GO:1903708 positive regulation of hemopoiesis IEP Predict GO terms from Neighborhoods
BP GO:1990542 mitochondrial transmembrane transport IEP Predict GO terms from Neighborhoods
BP GO:2000736 regulation of stem cell differentiation IEP Predict GO terms from Neighborhoods
BP GO:2000738 positive regulation of stem cell differentiation IEP Predict GO terms from Neighborhoods
BP GO:2000779 regulation of double-strand break repair IEP Predict GO terms from Neighborhoods
InterPro domains Description Start Stop
IPR023115 TIF_IF2_dom3 1038 1133
IPR027417 P-loop_NTPase 689 983
IPR036925 TIF_IF2_dom3_sf 1017 1147
IPR005225 Small_GTP-bd_dom 696 820
IPR009000 Transl_B-barrel_sf 1151 1283
IPR000795 T_Tr_GTP-bd_dom 695 904
IPR004161 EFTu-like_2 931 1009
No external refs found!