GO:0035195: miRNA-mediated gene silencing (Biological process)

"A post-transcriptional gene silencing pathway in which regulatory microRNAs (miRNAs) elicit silencing of specific target genes. miRNAs are endogenous 21-24 nucleotide small RNAs processed from stem-loop RNA precursors (pre-miRNAs). Once incorporated into a RNA-induced silencing complex (RISC), miRNAs can downregulate gene expression by either of two posttranscriptional mechanisms: endonucleolytic cleavage of the RNA (often mRNA) or mRNA translational repression, usually accompanied by poly-A tail shortening and subsequent degradation of the mRNA. miRNAs are present in all the animals and in plants, whereas siRNAs are present in lower animals and in plants." [GOC:aruk, GOC:bc, GOC:rl, PMID:14744438, PMID:15066275, PMID:15066283, PMID:23209154, PMID:23985560, PMID:28379604]


There are 529 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_102 Solanum tuberosum Agria 6.25 % 4e-06 0.000416
Cluster_9 Solanum tuberosum Agria 1.22 % 0.008325 0.049677
Cluster_673 Solanum tuberosum Agria 66.67 % 8e-06 7.6e-05
Cluster_110 Solanum tuberosum Agria 2.74 % 0.006831 0.024882
Cluster_24 Solanum tuberosum Agria 6.54 % 0.0 0.0
Sequences (529) (download table)

Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro Domains

Family Terms