GO:0036503: ERAD pathway (Biological process)

"The protein catabolic pathway which targets endoplasmic reticulum (ER)-resident proteins for degradation by the cytoplasmic proteasome. It begins with recognition of the ER-resident protein, includes retrotranslocation (dislocation) of the protein from the ER to the cytosol, protein modifications necessary for correct substrate transfer (e.g. ubiquitination), transport of the protein to the proteasome, and ends with degradation of the protein by the cytoplasmic proteasome." [GOC:bf, GOC:PARL, PMID:20940304, PMID:21969857]


There are 976 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_124 Solanum tuberosum Agria 2.06 % 0.006329 0.045614
Cluster_249 Solanum tuberosum Agria 5.49 % 2.5e-05 0.001021
Cluster_112 Solanum tuberosum Agria 5.71 % 0.000145 0.001207
Cluster_246 Solanum tuberosum Agria 5.36 % 0.001248 0.018673
Cluster_230 Solanum tuberosum Agria 2.44 % 0.003503 0.018388
Cluster_22 Solanum tuberosum Agria 5.74 % 0.0 0.000196
Cluster_262 Solanum tuberosum Agria 3.33 % 0.004821 0.035521
Cluster_763 Solanum tuberosum Agria 100.0 % 1.4e-05 0.000104
Cluster_203 Solanum tuberosum Agria 4.84 % 0.001675 0.028546
Cluster_119 Solanum tuberosum Agria 7.06 % 1e-06 2.1e-05
Cluster_248 Solanum tuberosum Agria 2.59 % 0.00969 0.049502
Cluster_81 Solanum tuberosum Agria 7.69 % 0.0 0.0
Sequences (976) (download table)

Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro Domains

Family Terms