SOLTUB.AGRIA.G00000014788

Description : Dna mismatch repair protein mlh1

Gene families : OG_02_0005895 (Orthogroups with 8 Potato genotypes) Phylogenetic Tree(s): No tree available for this family

Sequence : coding (download), protein (download)

Download

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR Network (HRR 50 & PCC 0.5): SOLTUB.AGRIA.G00000014788
Cluster	HCCA Clusters (HRR 50 & PCC 0.5): Cluster_118

Type	GO Term	Name	Evidence	Source
BP	GO:0000018	regulation of DNA recombination	None	Extended
BP	GO:0000019	regulation of mitotic recombination	None	Extended
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0000217	DNA secondary structure binding	None	Extended
BP	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening	IEA	AHRD
MF	GO:0000404	heteroduplex DNA loop binding	IEA	AHRD
MF	GO:0000405	bubble DNA binding	IEA	AHRD
BP	GO:0000712	resolution of meiotic recombination intermediates	IEA	AHRD
BP	GO:0000713	meiotic heteroduplex formation	IEA	AHRD
CC	GO:0000785	chromatin	IEA	AHRD
CC	GO:0000795	synaptonemal complex	IEA	AHRD
BP	GO:0000956	nuclear-transcribed mRNA catabolic process	None	Extended
BP	GO:0001666	response to hypoxia	IEA	AHRD
CC	GO:0001673	male germ cell nucleus	IEA	AHRD
BP	GO:0002200	somatic diversification of immune receptors	None	Extended
BP	GO:0002376	immune system process	None	Extended
BP	GO:0002566	somatic diversification of immune receptors via somatic mutation	None	Extended
BP	GO:0002637	regulation of immunoglobulin production	None	Extended
BP	GO:0002639	positive regulation of immunoglobulin production	None	Extended
BP	GO:0002682	regulation of immune system process	None	Extended
BP	GO:0002684	positive regulation of immune system process	None	Extended
BP	GO:0002694	regulation of leukocyte activation	None	Extended
BP	GO:0002696	positive regulation of leukocyte activation	None	Extended
BP	GO:0002697	regulation of immune effector process	None	Extended
BP	GO:0002699	positive regulation of immune effector process	None	Extended
BP	GO:0002700	regulation of production of molecular mediator of immune response	None	Extended
BP	GO:0002702	positive regulation of production of molecular mediator of immune response	None	Extended
BP	GO:0002703	regulation of leukocyte mediated immunity	None	Extended
BP	GO:0002705	positive regulation of leukocyte mediated immunity	None	Extended
BP	GO:0002706	regulation of lymphocyte mediated immunity	None	Extended
BP	GO:0002708	positive regulation of lymphocyte mediated immunity	None	Extended
BP	GO:0002712	regulation of B cell mediated immunity	None	Extended
BP	GO:0002714	positive regulation of B cell mediated immunity	None	Extended
BP	GO:0002819	regulation of adaptive immune response	None	Extended
BP	GO:0002821	positive regulation of adaptive immune response	None	Extended
BP	GO:0002822	regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	None	Extended
BP	GO:0002824	positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	None	Extended
BP	GO:0002889	regulation of immunoglobulin mediated immune response	None	Extended
BP	GO:0002891	positive regulation of immunoglobulin mediated immune response	None	Extended
BP	GO:0003006	developmental process involved in reproduction	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	None	Extended
MF	GO:0003682	chromatin binding	IEA	AHRD
MF	GO:0003690	double-stranded DNA binding	None	Extended
MF	GO:0003697	single-stranded DNA binding	IEA	AHRD
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005515	protein binding	None	Extended
MF	GO:0005524	ATP binding	IEA	AHRD
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005634	nucleus	None	Extended
CC	GO:0005654	nucleoplasm	IEA	AHRD
CC	GO:0005712	chiasma	IEA	AHRD
CC	GO:0005713	recombination nodule	None	Extended
CC	GO:0005715	late recombination nodule	IEA	AHRD
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006281	DNA repair	None	Extended
BP	GO:0006298	mismatch repair	IEA	AHRD
BP	GO:0006302	double-strand break repair	None	Extended
BP	GO:0006303	double-strand break repair via nonhomologous end joining	IEA	AHRD
BP	GO:0006401	RNA catabolic process	None	Extended
BP	GO:0006402	mRNA catabolic process	None	Extended
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006950	response to stress	None	Extended
BP	GO:0006974	cellular response to DNA damage stimulus	None	Extended
BP	GO:0006996	organelle organization	None	Extended
BP	GO:0007017	microtubule-based process	None	Extended
BP	GO:0007059	chromosome segregation	None	Extended
BP	GO:0007060	male meiosis chromosome segregation	IEA	AHRD
BP	GO:0007129	homologous chromosome pairing at meiosis	IEA	AHRD
BP	GO:0007165	signal transduction	None	Extended
BP	GO:0007275	multicellular organism development	None	Extended
BP	GO:0007276	gamete generation	None	Extended
BP	GO:0007281	germ cell development	None	Extended
BP	GO:0007283	spermatogenesis	IEA	AHRD
BP	GO:0007292	female gamete generation	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage	IEA	AHRD
BP	GO:0009056	catabolic process	None	Extended
BP	GO:0009057	macromolecule catabolic process	None	Extended
BP	GO:0009555	pollen development	IEA	AHRD
BP	GO:0009605	response to external stimulus	None	Extended
BP	GO:0009607	response to biotic stimulus	None	Extended
BP	GO:0009617	response to bacterium	IEA	AHRD
BP	GO:0009628	response to abiotic stimulus	None	Extended
BP	GO:0009636	response to toxic substance	IEA	AHRD
BP	GO:0009791	post-embryonic development	None	Extended
BP	GO:0009845	seed germination	IEA	AHRD
BP	GO:0009892	negative regulation of metabolic process	None	Extended
BP	GO:0009893	positive regulation of metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0010033	response to organic substance	None	Extended
BP	GO:0010468	regulation of gene expression	None	Extended
BP	GO:0010604	positive regulation of macromolecule metabolic process	None	Extended
BP	GO:0010605	negative regulation of macromolecule metabolic process	None	Extended
BP	GO:0010628	positive regulation of gene expression	None	Extended
BP	GO:0010629	negative regulation of gene expression	None	Extended
BP	GO:0014070	response to organic cyclic compound	None	Extended
BP	GO:0016043	cellular component organization	None	Extended
BP	GO:0016070	RNA metabolic process	None	Extended
BP	GO:0016071	mRNA metabolic process	None	Extended
BP	GO:0016321	female meiosis chromosome segregation	IEA	AHRD
BP	GO:0016445	somatic diversification of immunoglobulins	None	Extended
BP	GO:0016446	somatic hypermutation of immunoglobulin genes	IEA	AHRD
MF	GO:0016462	pyrophosphatase activity	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	None	Extended
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	None	Extended
MF	GO:0016887	ATP hydrolysis activity	IEA	AHRD
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0017111	ribonucleoside triphosphate phosphatase activity	None	Extended
BP	GO:0019219	regulation of nucleobase-containing compound metabolic process	None	Extended
BP	GO:0019222	regulation of metabolic process	None	Extended
BP	GO:0019439	aromatic compound catabolic process	None	Extended
MF	GO:0019899	enzyme binding	IEA	AHRD
BP	GO:0022402	cell cycle process	None	Extended
BP	GO:0022412	cellular process involved in reproduction in multicellular organism	None	Extended
BP	GO:0022414	reproductive process	None	Extended
BP	GO:0022607	cellular component assembly	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0030983	mismatched DNA binding	None	Extended
BP	GO:0031323	regulation of cellular metabolic process	None	Extended
BP	GO:0031324	negative regulation of cellular metabolic process	None	Extended
BP	GO:0031325	positive regulation of cellular metabolic process	None	Extended
MF	GO:0032135	DNA insertion or deletion binding	None	Extended
MF	GO:0032137	guanine/thymine mispair binding	IEA	AHRD
CC	GO:0032300	mismatch repair complex	None	Extended
CC	GO:0032389	MutLalpha complex	IEA	AHRD
MF	GO:0032404	mismatch repair complex binding	None	Extended
MF	GO:0032407	MutSalpha complex binding	IEA	AHRD
BP	GO:0032501	multicellular organismal process	None	Extended
BP	GO:0032502	developmental process	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
CC	GO:0032991	protein-containing complex	None	Extended
BP	GO:0033554	cellular response to stress	None	Extended
BP	GO:0034397	telomere localization	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0034655	nucleobase-containing compound catabolic process	None	Extended
BP	GO:0035556	intracellular signal transduction	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
BP	GO:0036293	response to decreased oxygen levels	None	Extended
BP	GO:0042221	response to chemical	None	Extended
BP	GO:0043060	meiotic metaphase I plate congression	IEA	AHRD
CC	GO:0043073	germ cell nucleus	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0043207	response to external biotic stimulus	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043231	intracellular membrane-bounded organelle	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044248	cellular catabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0044265	cellular macromolecule catabolic process	None	Extended
BP	GO:0044270	cellular nitrogen compound catabolic process	None	Extended
BP	GO:0044419	biological process involved in interspecies interaction between organisms	None	Extended
MF	GO:0044877	protein-containing complex binding	None	Extended
BP	GO:0045132	meiotic chromosome segregation	None	Extended
BP	GO:0045141	meiotic telomere clustering	IEA	AHRD
BP	GO:0045191	regulation of isotype switching	None	Extended
BP	GO:0045830	positive regulation of isotype switching	None	Extended
BP	GO:0045910	negative regulation of DNA recombination	None	Extended
BP	GO:0045911	positive regulation of DNA recombination	None	Extended
BP	GO:0045934	negative regulation of nucleobase-containing compound metabolic process	None	Extended
BP	GO:0045935	positive regulation of nucleobase-containing compound metabolic process	None	Extended
BP	GO:0045950	negative regulation of mitotic recombination	IEA	AHRD
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0046700	heterocycle catabolic process	None	Extended
BP	GO:0048229	gametophyte development	None	Extended
BP	GO:0048232	male gamete generation	None	Extended
BP	GO:0048296	regulation of isotype switching to IgA isotypes	None	Extended
BP	GO:0048298	positive regulation of isotype switching to IgA isotypes	IEA	AHRD
BP	GO:0048302	regulation of isotype switching to IgG isotypes	None	Extended
BP	GO:0048304	positive regulation of isotype switching to IgG isotypes	IEA	AHRD
BP	GO:0048316	seed development	IEA	AHRD
BP	GO:0048468	cell development	None	Extended
BP	GO:0048477	oogenesis	IEA	AHRD
BP	GO:0048518	positive regulation of biological process	None	Extended
BP	GO:0048519	negative regulation of biological process	None	Extended
BP	GO:0048522	positive regulation of cellular process	None	Extended
BP	GO:0048523	negative regulation of cellular process	None	Extended
BP	GO:0048583	regulation of response to stimulus	None	Extended
BP	GO:0048584	positive regulation of response to stimulus	None	Extended
BP	GO:0048608	reproductive structure development	None	Extended
BP	GO:0048609	multicellular organismal reproductive process	None	Extended
BP	GO:0048856	anatomical structure development	None	Extended
BP	GO:0048869	cellular developmental process	None	Extended
BP	GO:0050000	chromosome localization	None	Extended
BP	GO:0050776	regulation of immune response	None	Extended
BP	GO:0050778	positive regulation of immune response	None	Extended
BP	GO:0050789	regulation of biological process	None	Extended
BP	GO:0050793	regulation of developmental process	None	Extended
BP	GO:0050794	regulation of cellular process	None	Extended
BP	GO:0050864	regulation of B cell activation	None	Extended
BP	GO:0050865	regulation of cell activation	None	Extended
BP	GO:0050867	positive regulation of cell activation	None	Extended
BP	GO:0050871	positive regulation of B cell activation	None	Extended
BP	GO:0050896	response to stimulus	None	Extended
BP	GO:0051052	regulation of DNA metabolic process	None	Extended
BP	GO:0051053	negative regulation of DNA metabolic process	None	Extended
BP	GO:0051054	positive regulation of DNA metabolic process	None	Extended
BP	GO:0051094	positive regulation of developmental process	None	Extended
BP	GO:0051171	regulation of nitrogen compound metabolic process	None	Extended
BP	GO:0051172	negative regulation of nitrogen compound metabolic process	None	Extended
BP	GO:0051173	positive regulation of nitrogen compound metabolic process	None	Extended
BP	GO:0051179	localization	None	Extended
BP	GO:0051234	establishment of localization	None	Extended
BP	GO:0051239	regulation of multicellular organismal process	None	Extended
BP	GO:0051240	positive regulation of multicellular organismal process	None	Extended
BP	GO:0051249	regulation of lymphocyte activation	None	Extended
BP	GO:0051251	positive regulation of lymphocyte activation	None	Extended
BP	GO:0051255	spindle midzone assembly	None	Extended
BP	GO:0051257	meiotic spindle midzone assembly	IEA	AHRD
BP	GO:0051276	chromosome organization	None	Extended
BP	GO:0051303	establishment of chromosome localization	None	Extended
BP	GO:0051310	metaphase plate congression	None	Extended
BP	GO:0051311	meiotic metaphase plate congression	None	Extended
BP	GO:0051640	organelle localization	None	Extended
BP	GO:0051649	establishment of localization in cell	None	Extended
BP	GO:0051656	establishment of organelle localization	None	Extended
BP	GO:0051707	response to other organism	None	Extended
BP	GO:0051716	cellular response to stimulus	None	Extended
BP	GO:0060255	regulation of macromolecule metabolic process	None	Extended
BP	GO:0061982	meiosis I cell cycle process	None	Extended
BP	GO:0065007	biological regulation	None	Extended
BP	GO:0070192	chromosome organization involved in meiotic cell cycle	None	Extended
BP	GO:0070482	response to oxygen levels	None	Extended
BP	GO:0070887	cellular response to chemical stimulus	None	Extended
BP	GO:0071310	cellular response to organic substance	None	Extended
BP	GO:0071407	cellular response to organic cyclic compound	IEA	AHRD
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0071840	cellular component organization or biogenesis	None	Extended
BP	GO:0080090	regulation of primary metabolic process	None	Extended
BP	GO:0090220	chromosome localization to nuclear envelope involved in homologous chromosome segregation	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
BP	GO:0097190	apoptotic signaling pathway	None	Extended
BP	GO:0097193	intrinsic apoptotic signaling pathway	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
BP	GO:0098813	nuclear chromosome segregation	None	Extended
CC	GO:0099086	synaptonemal structure	None	Extended
CC	GO:0110165	cellular anatomical entity	None	Extended
CC	GO:0140513	nuclear protein-containing complex	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
BP	GO:1901361	organic cyclic compound catabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901575	organic substance catabolic process	None	Extended
BP	GO:1903046	meiotic cell cycle process	None	Extended

Toggle parental

Type	GO Term	Name	Evidence	Source
BP	GO:0000963	mitochondrial RNA processing	IEP	Predict GO terms from Neighborhoods
BP	GO:0000966	RNA 5'-end processing	IEP	Predict GO terms from Neighborhoods
MF	GO:0003916	DNA topoisomerase activity	IEP	Predict GO terms from Neighborhoods
MF	GO:0003918	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity	IEP	Predict GO terms from Neighborhoods
MF	GO:0004016	adenylate cyclase activity	IEP	Predict GO terms from Neighborhoods
BP	GO:0006195	purine nucleotide catabolic process	IEP	Predict GO terms from Neighborhoods
BP	GO:0006260	DNA replication	IEP	Predict GO terms from Neighborhoods
BP	GO:0006261	DNA-templated DNA replication	IEP	Predict GO terms from Neighborhoods
BP	GO:0006265	DNA topological change	IEP	Predict GO terms from Neighborhoods
BP	GO:0006396	RNA processing	IEP	Predict GO terms from Neighborhoods
BP	GO:0006723	cuticle hydrocarbon biosynthetic process	IEP	Predict GO terms from Neighborhoods
MF	GO:0008094	ATP-dependent activity, acting on DNA	IEP	Predict GO terms from Neighborhoods
MF	GO:0008252	nucleotidase activity	IEP	Predict GO terms from Neighborhoods
MF	GO:0008253	5'-nucleotidase activity	IEP	Predict GO terms from Neighborhoods
BP	GO:0009123	nucleoside monophosphate metabolic process	IEP	Predict GO terms from Neighborhoods
BP	GO:0009125	nucleoside monophosphate catabolic process	IEP	Predict GO terms from Neighborhoods
BP	GO:0009126	purine nucleoside monophosphate metabolic process	IEP	Predict GO terms from Neighborhoods
BP	GO:0009128	purine nucleoside monophosphate catabolic process	IEP	Predict GO terms from Neighborhoods
BP	GO:0009154	purine ribonucleotide catabolic process	IEP	Predict GO terms from Neighborhoods
BP	GO:0009158	ribonucleoside monophosphate catabolic process	IEP	Predict GO terms from Neighborhoods
BP	GO:0009161	ribonucleoside monophosphate metabolic process	IEP	Predict GO terms from Neighborhoods
BP	GO:0009166	nucleotide catabolic process	IEP	Predict GO terms from Neighborhoods
BP	GO:0009167	purine ribonucleoside monophosphate metabolic process	IEP	Predict GO terms from Neighborhoods
BP	GO:0009169	purine ribonucleoside monophosphate catabolic process	IEP	Predict GO terms from Neighborhoods
BP	GO:0009261	ribonucleotide catabolic process	IEP	Predict GO terms from Neighborhoods
CC	GO:0009330	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex	IEP	Predict GO terms from Neighborhoods
MF	GO:0009975	cyclase activity	IEP	Predict GO terms from Neighborhoods
BP	GO:0010026	trichome differentiation	IEP	Predict GO terms from Neighborhoods
CC	GO:0015935	small ribosomal subunit	IEP	Predict GO terms from Neighborhoods
MF	GO:0016780	phosphotransferase activity, for other substituted phosphate groups	IEP	Predict GO terms from Neighborhoods
MF	GO:0016849	phosphorus-oxygen lyase activity	IEP	Predict GO terms from Neighborhoods
BP	GO:0042023	DNA endoreduplication	IEP	Predict GO terms from Neighborhoods
BP	GO:0043446	cellular alkane metabolic process	IEP	Predict GO terms from Neighborhoods
BP	GO:0043447	alkane biosynthetic process	IEP	Predict GO terms from Neighborhoods
BP	GO:0044786	cell cycle DNA replication	IEP	Predict GO terms from Neighborhoods
MF	GO:0051267	CP2 mannose-ethanolamine phosphotransferase activity	IEP	Predict GO terms from Neighborhoods
MF	GO:0051377	mannose-ethanolamine phosphotransferase activity	IEP	Predict GO terms from Neighborhoods
BP	GO:0060147	regulation of post-transcriptional gene silencing	IEP	Predict GO terms from Neighborhoods
BP	GO:0060149	negative regulation of post-transcriptional gene silencing	IEP	Predict GO terms from Neighborhoods
BP	GO:0060966	regulation of gene silencing by RNA	IEP	Predict GO terms from Neighborhoods
BP	GO:0060967	negative regulation of gene silencing by RNA	IEP	Predict GO terms from Neighborhoods
BP	GO:0071103	DNA conformation change	IEP	Predict GO terms from Neighborhoods
BP	GO:0072523	purine-containing compound catabolic process	IEP	Predict GO terms from Neighborhoods
BP	GO:0080156	mitochondrial mRNA modification	IEP	Predict GO terms from Neighborhoods
BP	GO:0090615	mitochondrial mRNA processing	IEP	Predict GO terms from Neighborhoods
BP	GO:0090617	mitochondrial mRNA 5'-end processing	IEP	Predict GO terms from Neighborhoods
BP	GO:0140053	mitochondrial gene expression	IEP	Predict GO terms from Neighborhoods
BP	GO:1900368	regulation of post-transcriptional gene silencing by RNA	IEP	Predict GO terms from Neighborhoods
BP	GO:1900369	negative regulation of post-transcriptional gene silencing by RNA	IEP	Predict GO terms from Neighborhoods
BP	GO:1901136	carbohydrate derivative catabolic process	IEP	Predict GO terms from Neighborhoods
BP	GO:1901292	nucleoside phosphate catabolic process	IEP	Predict GO terms from Neighborhoods

InterPro domains	Description	Start	Stop
IPR032189	Mlh1_C	452	738
IPR020568	Ribosomal_S5_D2-typ_fold	220	358
IPR036890	HATPase_C_sf	27	240
IPR002099	DNA_mismatch_repair_N	27	337
IPR013507	DNA_mismatch_S5_2-like	236	357

External Links

No external refs found!

SOLTUB.AGRIA.G00000014788

Expression Profile

Co-expression Networks

Functional Annotation